Naveen Yadav, Sukhbir Lal Khokra, Sandeep Jain, Jile Singh Yadav
Naveen Yadav1*, Sukhbir Lal Khokra1, Sandeep Jain2 and Jile Singh Yadav2
1Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra
2Department of Pharmaceutical Sciences, GJUS and T, Hisar, Haryana
Volume - 4,
Issue - 11,
Year - 2011
An easy access to a series of 1,3,4-oxadiazoles bearing a 1-(naphthalen-2-yl)propan-1-one side chain in the 4-position is described. These compounds were obtained starting from commercially available Naphthalene and aromatic acids. The work involves Friedal craft acylation reaction of hydrocarbons i.e. Naphthalene that result in formation of Aroyl propanoic acid and finally this Aroyl propanoic acid is condensed with different aromatic hydrazides and result in formation of 1,3,4 –oxadiazoles. The resulted compounds were screened for their biological activity.
Cite this article:
Naveen Yadav, Sukhbir Lal Khokra, Sandeep Jain, Jile Singh Yadav. Synthesis, Characterization and Biological Evaluation of Novel 1,3,4-Oxadiazole Derivatives of 3-(2- napthoyl) propionic acid. Asian J. Research Chem. 4(11): Nov., 2011; Page 1755-1759.