In-process quality control parameters were developed for Ayurvedic formulation sitopaladi churna to produce reproducible results. During preparation each step like particle size (µm) of sitopaladi churna was found 0.019±0.001, 0.016?0.110 and 0.013±0.190 while angle of repose (?°) was estimated as 15.01±1.03, 13.03±0.18 and 13.01±1.01 respectively for CH-1, CH-2 and CH-3 and batch-to-batch coefficient of variance was found 0.0519 and 1.208 for particle size and angle of repose. Volatile oil content (%v/w) was estimated as 9.1±1.01, 12.2±1.13 and 12.1±0.03 respectively and 1.983 coefficient of variance. Total ash, acid insoluble and water soluble ash ((%w/w) ) was determined and it was found 22.5±1.13, 21.12±1.14 and 20.2±1.13, 4.1±0.03, 4.3±0.11 and 4.6±0.19, 12.6±1.11, 11.9±1.01 and 12.2±1.09 respectively and batch-to-batch coefficient of variance was found 2.253, 0.896 and 1.002. Batch-to-batch consistency and low coefficient of variance indicated uniformity of formulation which coded as CH-1, CH-2 and CH-3.
Cite this article:
Bharti Ahirwar. In-process quality control parameters of Ayurvedic formulation sitopaladi churna. Asian J. Research Chem. 5(12): Dec., 2012; Page 1457-1459.
Bharti Ahirwar. In-process quality control parameters of Ayurvedic formulation sitopaladi churna. Asian J. Research Chem. 5(12): Dec., 2012; Page 1457-1459. Available on: https://ajrconline.org/AbstractView.aspx?PID=2012-5-12-10