ABSTRACT:
5-bromo 2,3-diamino pyridine and ethylpyruvate react each other to form 7-bromo-2-methylpyrido[2,3-b]pyrazin-3-ol (1) which further reacts with ethylchloroacetate and formethyl 2-((7-bromo-2-methylpyrido[2,3-b]pyrazin-3-yl)oxy)acetate (2). Compound 2 on reaction with hydrazinehydrate gives 2-((7-bromo-2-methylpyrido[2,3-b]pyrazin-3-yl)oxy)acetohydrazide (3), which on condensation with different aldehydes produce N'-Arylidene-2-((7-bromo-2-methylpyrido[2,3-b]pyrazin-3-yl)oxy)acetohydrazides (4a-e).
Cite this article:
Rajeshwari M. Eco friendly synthesis of N'-Arylidene-2-((7-bromo-2-methylpyrido[2,3-B]pyrazin-3-yl)oxy)acetohydrazides. Asian J. Research Chem. 2018; 11(2):279-281. doi: 10.5958/0974-4150.2018.00052.4
Cite(Electronic):
Rajeshwari M. Eco friendly synthesis of N'-Arylidene-2-((7-bromo-2-methylpyrido[2,3-B]pyrazin-3-yl)oxy)acetohydrazides. Asian J. Research Chem. 2018; 11(2):279-281. doi: 10.5958/0974-4150.2018.00052.4 Available on: https://ajrconline.org/AbstractView.aspx?PID=2018-11-2-12