ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Mirza Shahed, Palaskar Pallavi S, MHG Dehghan, SN Mokale

Email(s): mirzashahed2@yahoo.co.in

DOI: Not Available

Address: Mirza Shahed*, Palaskar Pallavi S, MHG Dehghan and SN Mokale
Y.B. Chavan College of Pharmacy, Dr. Rafiq Zakaria Campus, Rauza Bagh, Aurangabad-431001
*Corresponding Author

Published In:   Volume - 2,      Issue - 4,     Year - 2009


ABSTRACT:
Two simple, accurate, precise, methods were developed for the estimation of Abacavir sulfate and Lamivudine in Tablet dosage form. Both the drugs are used against the HIV infection as reverse transcriptase inhibitors. Method A is Simultaneous equation method, wavelength selected for Quantitation are 284.0 nm and 270.0 nm for Abacavir sulfate (ABAC) and Lamivudine (LAM) respectively which are the ?max of both the drugs. Method B is Q –Analysis method, wavelength selected were 284.0 nm (?max of ABAC) and 265.0 nm (Isobestic point) for the analysis. In both the methods linearity for detector response was observed in the concentration range of 5-30 mcg/ml for ABAC and LAM respectively. The proposed methods were successfully applied for the simultaneous determination of both the drugs in commercial tablet preparation. The results of the analysis have been validated statistically and by recovery studies.


Cite this article:
Mirza Shahed, Palaskar Pallavi S, MHG Dehghan, SN Mokale. Simultaneous Spectrophotometric Estimation of Abacavir sulfate and Lamivudine in Tablet Dosage Form. Asian J. Research Chem. 2(4):Oct.-Dec. 2009 page 461-463.


Recomonded Articles:

Author(s): Jadhav S.D., Bhatia M.S., Thamake S.L., Pishawikar S.A.

DOI:         Access: Open Access Read More

Author(s): Mirza Shahed, Palaskar Pallavi S, MHG Dehghan, SN Mokale

DOI:         Access: Open Access Read More

Author(s): Lakshmi Aswini G., Dhachinamoorthi D., Prasada Rao CH.

DOI:         Access: Open Access Read More

Author(s): Ravi Prakash Mahor, Versha Parcha, Yogendra Singh, Rajiv Sharma, Anil Bhandari

DOI:         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags