ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Priya R. Modiya, Urviben Y. Patel, Ravi N. Patel, Dhrubo Jyoti Sen

Email(s): dhrubosen69@yahoo.com

DOI: Not Available

Address: Priya R. Modiya, Urviben Y. Patel, Ravi N. Patel and Dhrubo Jyoti Sen
Department of Pharmaceutical Chemistry, Shri Sarvajanik Pharmacy College, Gujarat Technological University, Arvind Baug, Mehsana-384001, Gujarat, India
*Corresponding Author

Published In:   Volume - 4,      Issue - 1,     Year - 2011


ABSTRACT:
Biological macromolecules are composed of one or more linear oligomers that fold into a functional form. The information that governs the final structure is encoded in the sequence of monomers and the precise functionality that they display, but accurate prediction of such structures remains a major challenge in structural biology. Recently, chemists have begun to develop small molecule systems that fold in a similar way and these may help to answer more complex questions or find applications in artificial molecular assemblies. Study of the properties of a family of oligoamides composed of alternating repeats of isophthalic acid and bisaniline building blocks have a rich supramolecular chemistry in non-polar solvents, forming macrocyclic receptors, catenanes, knots and double-stranded zipper complexes via a combination of amide–amide hydrogen bonds and aromatic interactions. Here the serendipitous discovery of a new member of the family that folds into a well-defined, compact, three-dimensional structure, governed by a combination of hydrogen bonding and aromatic interactions.


Cite this article:
Priya R. Modiya, Urviben Y. Patel, Ravi N. Patel, Dhrubo Jyoti Sen. Foldamers are Artificial Molecular Architectures Inspired by Biopolymers which can hold the Molecules in the Matrix by Non-Covalent Interactions. Asian J. Research Chem. 4(1): January 2011; Page 13-23.


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Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

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