Author(s):
Priya R. Modiya, Urviben Y. Patel, Ravi N. Patel, Dhrubo Jyoti Sen
Email(s):
dhrubosen69@yahoo.com
DOI:
Not Available
Address:
Priya R. Modiya, Urviben Y. Patel, Ravi N. Patel and Dhrubo Jyoti Sen
Department of Pharmaceutical Chemistry, Shri Sarvajanik Pharmacy College, Gujarat Technological University, Arvind Baug, Mehsana-384001, Gujarat, India
*Corresponding Author
Published In:
Volume - 4,
Issue - 1,
Year - 2011
ABSTRACT:
Biological macromolecules are composed of one or more linear oligomers that fold into a functional form. The information that governs the final structure is encoded in the sequence of monomers and the precise functionality that they display, but accurate prediction of such structures remains a major challenge in structural biology. Recently, chemists have begun to develop small molecule systems that fold in a similar way and these may help to answer more complex questions or find applications in artificial molecular assemblies. Study of the properties of a family of oligoamides composed of alternating repeats of isophthalic acid and bisaniline building blocks have a rich supramolecular chemistry in non-polar solvents, forming macrocyclic receptors, catenanes, knots and double-stranded zipper complexes via a combination of amide–amide hydrogen bonds and aromatic interactions. Here the serendipitous discovery of a new member of the family that folds into a well-defined, compact, three-dimensional structure, governed by a combination of hydrogen bonding and aromatic interactions.
Cite this article:
Priya R. Modiya, Urviben Y. Patel, Ravi N. Patel, Dhrubo Jyoti Sen. Foldamers are Artificial Molecular Architectures Inspired by Biopolymers which can hold the Molecules in the Matrix by Non-Covalent Interactions. Asian J. Research Chem. 4(1): January 2011; Page 13-23.
Cite(Electronic):
Priya R. Modiya, Urviben Y. Patel, Ravi N. Patel, Dhrubo Jyoti Sen. Foldamers are Artificial Molecular Architectures Inspired by Biopolymers which can hold the Molecules in the Matrix by Non-Covalent Interactions. Asian J. Research Chem. 4(1): January 2011; Page 13-23. Available on: https://ajrconline.org/AbstractView.aspx?PID=2011-4-1-2