Consecutive SN2 reaction of a-chloro nitrones are studied with isopropyl halides and the nitrones are found to have remarkable oxidizing properties for the conversion of isopropyl halides to ketones with high yields. In addition, the side product obtained can serve as efficient dipolarophile in 1,3-Dipolar cycloaddition reaction to produce spiro cycloadduct in good yield.
Cite this article:
Bhaskar Chakraborty, Prawin K. Sharma. New and Efficient Route for the Synthesis of Ketone from Alkyl Halide Using α-Chloro Nitrone as Oxidizing Reagent. Asian J. Research Chem. 4(1): January 2011; Page 95-99.