ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Gawai Mamata N, Aher Smita S, Saudager Ravindra B.

Email(s): rbs36@rediffmail.com

DOI: 10.5958/0974-4150.2016.00066.3   

Address: Gawai Mamata N1*, Aher Smita S2, Saudager Ravindra B.3
1Department of Quality Assurance Techniques, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India
2Department of Analytical Chemistry, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik- 422213, Maharashtra, India.
3Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy, Anjeneri, Nashik- 422213, Maharashtra, India
*Corresponding Author

Published In:   Volume - 9,      Issue - 9,     Year - 2016


ABSTRACT:
Simple precise accurate UV Spectroscopic method has been developed and validated for estimation of valsartan in bulk and pharmaceutical dosage form. It is approved for the treatment of hypertension. It is an angiotensin II receptor antagonist. UV Spectroscopic method which is based on measurement of absorption of UV light, the spectra of valsartan in Phosphate buffer PH 7.4 showed maximum wavelength at 250 nm and calibration curve were plotted over the concentrations ranging from 2-20µg/ml of valsartan with correlation coefficient 0.9996 validation was performed as per ICH Q2 (R1) guidelines for linearity, accuracy, precision and recovery. The limit of detection (LOD) and limit of quantification (LOQ) were found to be 0.1229 and 0.3725 respectively by simple UV Spectroscopy .The proposed method was validated.


Cite this article:
Gawai Mamata N, Aher Smita S, Saudager Ravindra B.. New UV – Spectrophotometric Method Development and Validation of Valsartan in Bulk and Pharmaceutical Dosage Forms. Asian J. Research Chem. 2016; 9(9): 441-444. doi: 10.5958/0974-4150.2016.00066.3


Recomonded Articles:

Author(s): Arun Kumar, Vinita Gupta, Sanchita Singh, Y.K. Gupta

DOI: 10.5958/0974-4150.2017.00038.4         Access: Open Access Read More

Author(s): Y. Padmavathi, Akari Anjali, Nayaka Raghavendra Babu, P Ravi Kumar

DOI: 10.5958/0974-4150.2017.00064.5         Access: Open Access Read More

Author(s): Vatchavai Bhaskara Raju, Bonthu Mohan Gandhi, Kamatham Srinivas Sumanth, Kolli Srinivas, Tupakula N Venkata Lakshmi Neeraja

DOI: 10.5958/0974-4150.2017.00030.X         Access: Open Access Read More

Author(s): Alka Verma, Bhupesh Verma, Sunil Kumar Prajapati, Kishu Tripathi

DOI:         Access: Open Access Read More

Author(s): SS Chitlange, Kiran Bagri, DM Sakarkar

DOI:         Access: Open Access Read More

Author(s): Banerjee S, Bonde CG, Merukar SS, Patil YR

DOI:         Access: Open Access Read More

Author(s): PA Jadhav, CS Raut, JP Bidada, BB Buwa, PN Dhabale, SC Dhawale

DOI:         Access: Open Access Read More

Author(s): Manorama B. Motegaonkar, S. D. Salunke

DOI: 10.5958/0974-4150.2017.00025.6         Access: Open Access Read More

Author(s): Trapti Rastogi, Vijay Bhutda, Komal Moon, PB Aswar, SS Khadabadi

DOI:         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags