BS Vikram, T Srinivas Rao, K Ramesh
BS Vikram*, T Srinivas Rao and K Ramesh
Karnataka College of Pharmacy, 33/2, Thirumenahalli,Hegde Nagar Main Road,Yelahanka Hobli, Jakkur Post, Bangalore-560064 India
Volume - 2,
Issue - 3,
Year - 2009
Pyrazoline derivatives are found to be chemotherapeutically active and they are found to possess anti-inflammatory, anti-bacterial, anti-viral and analgesic activities. The objective of the dissertation work is to synthesize and characterization of 3,5-di-substituted pyrazolines and also to study their anti-bacterial activities.The method followed to synthesize 3,5 di-substituted pyrazolines are as follows: The results have shown that the 3,5 di-substituted pyrazoline derivatives are found to be effective anti-bacterial agents. The synthesized compounds were elucidated by spectral data. By analysis of IR, NMR and MASS spectral data the compounds reveals the successful information of 3,5-di-substituted pyrazolines and also about different aromatic groups at position 3 and 5.The synthesized compounds were screened for their anti-bacterial activities by using standard as ampicilin and are found to be effective chemotherapeutic agent. The synthesis of pyrazolines by the described methods resulted in the products with good yield.
Cite this article:
BS Vikram, T Srinivas Rao, K Ramesh. Synthesis and in Vitro Antimicrobial Activity of some New 3, 5 di-substituted pyrazoline derivatives. Asian J. Research Chem. 2(3): July-Sept., 2009, page 285-288.