Pankaj Gupta, Hardwari Lal Yadav, G. Garg, R.S. Pawar, U.K. Patil, P.K. Singour
Pankaj Gupta, Hardwari Lal Yadav, G. Garg, R.S. Pawar, U.K. Patil and P.K. Singour*:
Department of Pharmaceutical Chemistry, VNS Institute of Pharmacy, Neelbud, Bhopal, M.P, 462044, India
Volume - 3,
Issue - 1,
Year - 2010
A series of 1-(2/4-substituted-benzoyl)-3-benzothiazol-2-yl-thiourea were synthesized from benzothiazol-2-yl-amine and 2/4-substituted benzoylisothiocyanates in satisfactory yields. The newly synthesized compounds were characterized by UV, IR, and 1H-NMR spectroscopy. The synthesized compounds were evaluated for analgesic activity by hot plate method using aspirin (100mg/kg) as standard compound. The results highlights that the some compound shows significant analgesic activity.
Cite this article:
Pankaj Gupta, Hardwari Lal Yadav, G. Garg, R.S. Pawar, U.K. Patil, P.K. Singour. Synthesis and Biological Evaluation of Some Novel 2-Aminobenzothiazole Derivatives as Potential Analgesic Agents. Asian J. Research Chem. 3(1): Jan.-Mar. 2010; Page 47-50.