Author(s):
G. Muhubhupathi, M. Selvakumar, K. Mohanapriya, T. Brindha, B. Brindha Sri, Y. Mahalakshmi, P. Gayathri
Email(s):
muthubhupathi@gmail.com
DOI:
10.52711/0974-4150.2025.00008 
Address:
G. Muhubhupathi*, M. Selvakumar, K. Mohanapriya, T. Brindha, B. Brindha Sri, Y. Mahalakshmi, P. Gayathri
Department of Pharmaceutical Chemistry, Vivekanandha Pharmacy College for Women, Sankari, Salem - 637303. Tamil Nadu, India
*Corresponding Author
Published In:
Volume - 18,
Issue - 1,
Year - 2025
ABSTRACT:
The field of pharmaceutical chemistry is continuously evolving to address the challenges of modern drug discovery and development. This review explores novel chemical scaffolds in potency, specificity, and toxicity of imidazolidine and its derivatives. Imidazolidine, a heterocyclic organic compound has garnered significant attention in the field of synthetic and medicinal chemistry due to its versatile chemical structure and reactivity. This compound, consisting of two nitrogen atoms in five-memberedrings, serves as a core scaffold in synthesizing various pharmaceuticals, agrochemicals, and industrial materials. Research on the biological activity and synthesis of imidazolidine derivatives, conducted by numerous scientists worldwide, is published. The various pharmacological characteristics of imidazolidine derivatives are highlighted in this review. Meanwhile, target structures known as imidazolidine derivatives have been created and have shown a wide range of biological functions including anti-cancer, anti-proliferative, anti-psychotropic, anti-convulsant, anti-arrhythmic, anti-microbial, anti-plasmodial. Giving mechanistic insights into the specified atypical scaffolds that have found uses in contemporary medicinal chemistry are primarily derived from the literature of the past five years.
Cite this article:
G. Muhubhupathi, M. Selvakumar, K. Mohanapriya, T. Brindha, B. Brindha Sri, Y. Mahalakshmi, P. Gayathri. Imidazolidine Derivatives: A Comprehensive Review of their Biological Activities and Therapeutic Potential. Asian Journal of Research in Chemistry. 2025; 18(1):41-1. doi: 10.52711/0974-4150.2025.00008
Cite(Electronic):
G. Muhubhupathi, M. Selvakumar, K. Mohanapriya, T. Brindha, B. Brindha Sri, Y. Mahalakshmi, P. Gayathri. Imidazolidine Derivatives: A Comprehensive Review of their Biological Activities and Therapeutic Potential. Asian Journal of Research in Chemistry. 2025; 18(1):41-1. doi: 10.52711/0974-4150.2025.00008 Available on: https://ajrconline.org/AbstractView.aspx?PID=2025-18-1-8
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