ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Jacob Jincy, Dey Tathagata, Ghate Manjunath, Baby Shaji

Email(s): tathagata_d@rediffmail.com

DOI: Not Available

Address: Jacob Jincy1, Dey Tathagata1*, Ghate Manjunath2 and Baby Shaji3
1East Point College of Pharmacy, Bidarahalli, Virgonagar Post, Bangalore- 560049
2Krupanidhi College of Pharmacy, Chikkabelandur, Carmelaram Post, Varthur Hobli, Bangalore-560035
3Badar Al Samaa Hospital, P.O Box-516, P C-321, Barka, Sultanate of Oman
*Corresponding Author

Published In:   Volume - 3,      Issue - 1,     Year - 2010


ABSTRACT:
A series of eight coumarino benzimidazoles have been synthesized from 4-fluro-3-nitrobenzoic acid with the help of a supporting polymer PEG5000 and with suitable reagents. These compounds have then been subjected to preliminary anti-inflammatory screening using formaline induce rat paw oedema model. All the synthesized compounds have activity comparable to indomethacin (20 mg/kg) by intraperitonial route.


Cite this article:
Jacob Jincy, Dey Tathagata, Ghate Manjunath, Baby Shaji. Synthesis of Some Novel Coumarino Benzimidazoles Derivatives for Anti-Inflammatory Screening. Asian J. Research Chem. 3(1): Jan.-Mar. 2010; Page 116-120.


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