The dimeric steroids have been shown to exhibit such unique characteristics as detergents, medicinal, catalytic and liquid crystal properties that will lead to important applications. New dimeric steroids 1,3 (bicholest-5-enyl-3,3'-dioxy) propane (5) and 1,3 (bistigmasta-5,22-dienyl-3,3'-dioxy) propane (6) along with cholesta-4,6-diene (7) and stigmasta-4,6,22-triene (8) are synthesized by the treatment of acetic acid and CuCl2 with 1,3-dibromopropane which is proving to be a good reagent for such dimerizations. The structures (5) and (6) are supported by their physical and spectral properties (IR, 1HNMR, C13NMR and mass) and Rast’s method.
Cite this article:
M. Mushfiq, Sultanat Rakhshanda Rehman. Synthesis of Dimeric Steroids Using Cupric Chloride and 1, 3- Dibromopropane. Asian J. Research Chem. 3(3): July- Sept. 2010; Page 758-762.