A series of 5-halogen substituted 2, 4-(1H, 3H)Pyrimidinedione compounds have been synthesized by an effective, rapid microwave assisted method. The structures of compounds have been elucidated with UV, FTIR, GC-Mass spectrometer, solubility and melting points of compounds were determined. The antibacterial, antifungal and antiviral screening against B.subtilis, S.aureus, E.coli, A.nigar, A.flavus and ND virus revealed their significant activities.
Cite this article:
Shahana Ehsan, Bushra Khan. Conventional and Microwave-assisted Synthesis of 5-Halogeno-(X) 2, 4-(1H, 3H) Pyrimidinedione and Their Biological Evaluation. Asian J. Research Chem. 3(4): Oct. - Dec. 2010; Page 1103-1106.