ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Anna Pratima Nikalje, Pankaj Malhotra, Mangesh Ghodke

Email(s): ana@k.st

DOI: Not Available

Address: Anna Pratima Nikalje*, Pankaj Malhotra and Mangesh Ghodke
Department of Pharmaceutical Chemistry, Y. B. Chavan College of Pharmacy, Dr.Rafiq Zakaria Campus, Rauza Bagh, P.B. No. 33 Aurangabad (M.S.) 431001 INDIA.
*Corresponding Author

Published In:   Volume - 4,      Issue - 11,     Year - 2011


ABSTRACT:
A simple, efficient and green procedure has been developed for the synthesis of novel of 4-(3, 5-diarylsubstituted)-4,5-dihydro-1H-pyrazol-1-yl) benzene sulfonamides using ultrasonic irradiation. The present methodology offers several advantages such as excellent yields, simple procedure, short reaction times and milder conditions. A mixture of substituted prop-2-en-1-ones, 4-hydrazinylbenzenesulfonamide hydrochloride and hydrazine hydrate in ethanol and acetic acid was irradiated under ultrasound in an open vessel. The synthesized pyrazolines containing benzenesulphonamide group were evaluated for their anti-inflammatory activity using Carrageenan-induced rat hind paw oedema and have shown promising t anti-inflammatory activity.


Cite this article:
Anna Pratima Nikalje, Pankaj Malhotra, Mangesh Ghodke. Ultrasound-promoted Green Synthesis and Pharmacological Screening of Some Novel 4-(3, 5-diaryl substituted)-4,5-dihydro-1H-pyrazol-1-yl ) Benzene Sulfonamide. Asian J. Research Chem. 4(11): Nov., 2011; Page 1712-1716.


Recomonded Articles:

Author(s): Pankaj Baboo, Girendra Gautam, S.K. Gupta

DOI: 10.5958/0974-4150.2017.00039.6         Access: Open Access Read More

Author(s): KP Bhusari, ND Amnerkar, PB Khedekar, MK Kale, RP Bhole

DOI:         Access: Open Access Read More

Author(s): SR Pattan, NS Dighe, SA Nirmal, AN Merekar, RB Laware, HV Shinde, DS Musmade

DOI:         Access: Open Access Read More

Author(s): Hunasnalkar Shivraj G, Shaikh Gazi, Patil SM, Surwase Ulhas S

DOI:         Access: Open Access Read More

Author(s): Sapna Tyagi, Tanveer Alam, Mohd Azhar Khan, Hina Tarannum, Neha Chauhan

DOI: 10.5958/0974-4150.2018.00092.5         Access: Open Access Read More

Author(s): Anshul Sinha, A. K. Meena, P. Panda, Bhavana Srivastava, M. D. Gupta, M. M. Padhi

DOI:         Access: Open Access Read More

Author(s): Alok Singh Thakur, Parmanand Verma, Anish Chandy

DOI:         Access: Open Access Read More

Author(s): Sabale Prafulla, Potey Lata, Rahangdale Priya, Sabale Vidya

DOI: 10.5958/0974-4150.2019.00011.7         Access: Open Access Read More

Author(s): A.K. Meena, M.M. Rao, Kiran Sharma, Ajay Yadav, Uttam Singh, Amit

DOI:         Access: Open Access Read More

Author(s): BS Vikram, T Srinivas Rao, K Ramesh

DOI:         Access: Open Access Read More

Author(s): N. V. S. Venugopal, V. Nageswara Raoand, B. Sumalatha

DOI:         Access: Open Access Read More

Author(s): Shashi Ravi Suman Rudrangi, Vijaya Kumar Bontha, Venkata Reddy Manda, Srinivas Bethi

DOI:         Access: Open Access Read More

Author(s): Merlin NJ, Parthasarathy V, Manavalan R, Devi P, Meera R

DOI:         Access: Open Access Read More

Author(s): Kishore Kumar Valluri, Tejeswara Rao Allaka, I V Kasi Viswanath, Nagaraju PVVS

DOI: 10.5958/0974-4150.2018.00111.6         Access: Open Access Read More

Author(s): Jacob Jincy, Dey Tathagata, Ghate Manjunath, Baby Shaji

DOI:         Access: Open Access Read More

Author(s): P.A. Patil, R.P. Bhole, R.V. Chikhale, K.P. Bhusari, Amol Chandekar

DOI:         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags