Asian Journal of Research in Chemistry

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0974-4150 (Online)
0974-4169 (Print)


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Spectrophotometric Determination of Drugs Using p-Chloranilic Acid as Analytical Reagent

Author(s): K. Damodar Reddy, Sayaji Rao, G. Venkateshwarlu

Email(s): venkateshwarlugoud@yahoo.com

DOI: Not Available

Address: K. Damodar Reddy, Sayaji Rao and G. Venkateshwarlu*
Department of Chemistry, Nizam College. Hyderabad, 500 001, India
*Corresponding Author

Published In:   Volume - 4,      Issue - 8,     Year - 2011

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ABSTRACT:
Six drugs viz., Metoprolol tartrate, Torsemide, Diclofenac sodium, Chlorpheniramine, Loratadine and irbesartan were tested for the formation of charge transfer complexes with p-CA and the interaction formed a basis for quantitative determination of the drugs spectrophotometrically. CH3CN was found to be suitable for the analysis. The methods have been validated in terms of ICH guidelunes The complexes were found to have 1:1 composition and have stability of the order 10 5.


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Cite this article:
K. Damodar Reddy, Sayaji Rao, G. Venkateshwarlu. Spectrophotometric Determination of Drugs Using p-Chloranilic Acid as Analytical Reagent. Asian J. Research Chem. 4(8): August, 2011; Page 1311-1317.


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Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

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Asian Journal of Research in Chemistry (AJRC) (ISSN: print-0974-4169, Online-0974-4150) is an international, peer-reviewed journal devoted to pure and applied chemistry. AJRC publishes Original Research Articles, Short Communications, Review Articles in all aspects of chemistry. Topics covered including the traditional areas of analytical, inorganic, organic, biochemistry, forensic, physical-theoretical chemistry as well as newer interdisciplinary areas such as agriculture, materials science, computational, medicine, spectroscopy, polymers, supramolecular, surface, chemical physics, biological, medicinal/ drugs, environmental and pharmaceutical chemistry.
The journal is published quarterly every year in last week of March, June, September and December. From January 2011, is monthly and shall be published every year in last week of Month.    
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