ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Napa Delhiraj, Sockalingam Anbazhagan

Email(s): pharmaraj1981@gmail.com

DOI: Not Available

Address: Napa Delhiraj1*, Sockalingam Anbazhagan2
1Research Scholar, Department of Pharmacy, Aacharya Nagarjuna University, Nagarjuna Nagar, Guntur, Andhra Pradesh, India
2Department of Pharmaceutical Analysis, Karuna College of Pharmacy, Iringuttoor, Kerala, India
*Corresponding Author

Published In:   Volume - 5,      Issue - 11,     Year - 2012


ABSTRACT:
A new, rapid, precise, accurate and specific chromatographic methods for the simultaneous determination of Telmisartan and Amlodipine in combined pharmaceutical dosage forms by utilizing silica gel 60F254 high performance thin layer chromatography and densitometric detection at 251nm using chloroform : methanol:formic acid (8.5:1.5:0.5) as the mobile phase. Maximum separation was achieved (Amlodipine Rf 0.47, Telmisartan Rf 0.61) and minimum tailing were obtained and also shows that correlation coefficients were 0.998 for Amlodipine and 0.997 for Telmisartan. The LOD values were 200 ng/spot and 100 ng/spot, while LOQ values were 600 ng/spot and 300 ng/spot for both Amlodipine and Telmisartan respectively. The method was accurate, precise, rapid and found to be suitable for the quantitative analysis of the drug and its dosage form.


Cite this article:
Napa Delhiraj, Sockalingam Anbazhagan. Validated HPTLC Method for the Estimation of Antihypertensive Drugs in Pharmaceutical Combined Dosage Forms. Asian J. Research Chem. 5(11): Nov., 2012; Page 1385-1387.

Cite(Electronic):
Napa Delhiraj, Sockalingam Anbazhagan. Validated HPTLC Method for the Estimation of Antihypertensive Drugs in Pharmaceutical Combined Dosage Forms. Asian J. Research Chem. 5(11): Nov., 2012; Page 1385-1387.   Available on: https://ajrconline.org/AbstractView.aspx?PID=2012-5-11-13


Recomonded Articles:

Author(s): Kateryna Taran, Ayaou Abderrahim, Vera Kravchenko, Olena Novosel, Svitlana Taran

DOI: 10.5958/0974-4150.2020.00034.6         Access: Open Access Read More

Author(s): Y. Padmavathi, Akari Anjali, Nayaka Raghavendra Babu, P Ravi Kumar

DOI: 10.5958/0974-4150.2017.00064.5         Access: Open Access Read More

Author(s): Tauseef Shaikh, Atar Mujum , Khan Wasimuzzama, Rukhsana A Rub

DOI:         Access: Open Access Read More

Author(s): Vatchavai Bhaskara Raju, Bonthu Mohan Gandhi, Kamatham Srinivas Sumanth, Kolli Srinivas, Tupakula N Venkata Lakshmi Neeraja

DOI: 10.5958/0974-4150.2017.00030.X         Access: Open Access Read More

Author(s): Alka Verma, Bhupesh Verma, Sunil Kumar Prajapati, Kishu Tripathi

DOI:         Access: Open Access Read More

Author(s): SS Chitlange, Kiran Bagri, DM Sakarkar

DOI:         Access: Open Access Read More

Author(s): Banerjee S, Bonde CG, Merukar SS, Patil YR

DOI:         Access: Open Access Read More

Author(s): Tentu Nageswara Rao, Muralidhar Reddy Avuthu, B. Venkata Reddy, SNVS Murthy

DOI: 10.5958/0974-4150.2016.00076.6         Access: Open Access Read More

Author(s): B. Balaswami, P. Venkata Ramana, B. Subba Rao, P. Sanjeeva

DOI: 10.5958/0974-4150.2018.00023.8         Access: Open Access Read More

Author(s): Sravani A

DOI: 10.5958/0974-4150.2018.00144.X         Access: Open Access Read More

Author(s): Prasanna Reddy Battu, MS Reddy

DOI:         Access: Open Access Read More

Author(s): PA Jadhav, CS Raut, JP Bidada, BB Buwa, PN Dhabale, SC Dhawale

DOI:         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags