The chemistry of metal complexes with tailor made Schiff base ligands and their applications have aroused considerable interest because of preparative accessibility, diverse reactivity and structural variability. A novel Schiff base ligand OHAPPTH (p-Toulic Hydrazide and o-Hydroxy acetophenone Schiff base) and its Mn (II), Co (II), Ni (II) and Cu (II) metal complexes have been synthesized and characterized by various physio chemical methods viz. FT-IR, H1-NMR, UV-Visible, ESR, VSM, Molar conductance, XRD and micro analytical data and found to be anti bacterial activity. The magnetic properties of these Mn (II), Co (II), Ni (II) and Cu (II) complexes are 5.25 B.M. 4.80 B.M., 3.06 B.M and 1.68 B.M respectively. This result clearly indicates that the metal complexes of this ligand show octahedral geometry. The IR spectrums of these Schiff base metal complexes shows bands at 1603cm-1, 1588cm-1 1612cm-1 and 1598cm-1 respectively, which is assigned to (C=N) stretching vibrations, a fundamental feature of azomethine group. The structural assessment of these complexes has been carried out based on above physio-chemical and spectroscopic methods. These Schiff base and its metal complexes show a good activity against E. coli and Basillus subtiles. The anti bacterial results also indicate that the metal complexes are better antibacterial agents as compare to the Schiff base.
Cite this article:
G.N. Raja Reddy, S. Kondaiah, J. Sree Ramulu. Synthesis and characterization of p-Toluic hydrazide and o-Hydroxy Acetophenone Schiff base and its metal complexes. Asian J. Research Chem. 5(3): March 2012; Page 358-364.