ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Dwivedi Abha, Kaushik Avinash, Sharma Ganesh N., Akhtar Javed

Email(s): dwivedi1409@hotmail.com

DOI: Not Available

Address: Dwivedi Abha*, Kaushik Avinash, Sharma Ganesh N., Akhtar Javed
School of Pharmaceutical Sciences, Jaipur National University, Jagatpura, Jaipur-302017.
*Corresponding Author

Published In:   Volume - 5,      Issue - 7,     Year - 2012


ABSTRACT:
Impurity profiling is very important for the identification source, types, structure elucidation and quantitative determination of organic and inorganic impurities in the dosage form and bulk drugs. Presence of these impurities affects the pharmacological property, stability of the formulation. So with the increase demand of the purity of product number of analytical methods have been developed. Identification of the impurities are done by chromatographic, spectroscopic and with the hyphenated techniques. Hyphenated techniques are widely used in impurity profiling as it has revolutionized the impurity profiling by not only the separation but structural identification of the impurities. The hyphenated techniques which are widely used are LC-NMR, LC-MS-MS, GC-MS, and LC-FTIR etc.


Cite this article:
Dwivedi Abha, Kaushik Avinash, Sharma Ganesh N., Akhtar Javed. Impurity Profiling With Use of Hyphenated Techniques. Asian J. Research Chem. 5(7): July, 2012; Page 875-881.

Cite(Electronic):
Dwivedi Abha, Kaushik Avinash, Sharma Ganesh N., Akhtar Javed. Impurity Profiling With Use of Hyphenated Techniques. Asian J. Research Chem. 5(7): July, 2012; Page 875-881.   Available on: https://ajrconline.org/AbstractView.aspx?PID=2012-5-7-13


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