ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): H.N. Khan, Chopde Asha, Mahajan Swarali, Md Zameeruddin, V.B. Bharkad

Email(s): khan.hajera@rediff.com

DOI: 10.5958/0974-4150.2018.00009.3   

Address: H.N. Khan*,Chopde Asha, Mahajan Swarali, Md Zameeruddin, V.B. Bharkad
Department of Quality Assurance, Indira college of Pharmacy, Vishnupuri, Nanded-431606 Maharashtra India
*Corresponding Author

Published In:   Volume - 11,      Issue - 1,     Year - 2018


ABSTRACT:
A simple, rapid, economical, precise and accurate Area under curve method was developed for determination of Clonidine HCl in bulk and pharmaceutical dosage form. The ethanol was used as solvent. The wavelength ranges selected for the analysis was 201-211nm. The Linearity was found to be between 1-5µg/ml. The % assay for commercial formulation was found to be in the range 99.93% – 100.03 %. Recovery was found in the range of 99.94 –99.97%. The results of analysis have been validated statistically and recovery studies confirmed the accuracy and reproducibility of the proposed methods which were carried out by following ICH guidelines.


Cite this article:
H.N. Khan, Chopde Asha, Mahajan Swarali, Md Zameeruddin, V.B. Bharkad. Development and Validation of Area under curve Method for the Estimation of Clonidine HCl in Bulk and Pharmaceutical dosage form. Asian J. Research Chem. 2018; 11(1):40-42. doi: 10.5958/0974-4150.2018.00009.3


Recomonded Articles:

Author(s): Bulusu Lakshmi Sushma1, Gutta Madhusudhan, Anireddy Jayashree

DOI: 10.5958/0974-4150.2017.00014.1         Access: Open Access Read More

Author(s): Y. Padmavathi, Akari Anjali, Nayaka Raghavendra Babu, P Ravi Kumar

DOI: 10.5958/0974-4150.2017.00064.5         Access: Open Access Read More

Author(s): Vatchavai Bhaskara Raju, Bonthu Mohan Gandhi, Kamatham Srinivas Sumanth, Kolli Srinivas, Tupakula N Venkata Lakshmi Neeraja

DOI: 10.5958/0974-4150.2017.00030.X         Access: Open Access Read More

Author(s): Alka Verma, Bhupesh Verma, Sunil Kumar Prajapati, Kishu Tripathi

DOI:         Access: Open Access Read More

Author(s): Mukund Nagarnaik, Arun Sarjoshi, Ajay Bodkhe, Bhupendra Khanal, Mayuri Pise, Girish Pandya

DOI: 10.5958/0974-4150.2015.00102.9         Access: Open Access Read More

Author(s): Banerjee S, Bonde CG, Merukar SS, Patil YR

DOI:         Access: Open Access Read More

Author(s): B. Balaswami, P. Venkata Ramana, B. Subba Rao, P. Sanjeeva

DOI: 10.5958/0974-4150.2018.00023.8         Access: Open Access Read More

Author(s): Tentu Nageswara Rao, Muralidhar Reddy Avuthu, B. Venkata Reddy, SNVS Murthy

DOI: 10.5958/0974-4150.2016.00076.6         Access: Open Access Read More

Author(s): Prasanna Reddy Battu, MS Reddy

DOI:         Access: Open Access Read More

Author(s): Ismail, R Rajavel, M Ganesh, M Jagadeeswaran, K Srinivasan, J Valarmathi, T Sivakumar

DOI:         Access: Open Access Read More

Author(s): PA Jadhav, CS Raut, JP Bidada, BB Buwa, PN Dhabale, SC Dhawale

DOI:         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags