ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Neha Subhash Patil, Sachin H. Rohane

Email(s): nehap2761@gmail.com

DOI: 10.5958/0974-4150.2021.00027.4   

Address: Neha Subhash Patil*, Sachin H. Rohane
Department of B. Pharmacy at Yashoda Technical Campus, Satara.
*Corresponding Author

Published In:   Volume - 14,      Issue - 2,     Year - 2021


ABSTRACT:
In the present era, many fields of research are showing great importance. Apart from the applications researchers have grown their interest in pharmaceutical application. Protein play and important side in study of various in - vitro and in - vivo studies to understand the action of drugs. Docking programs have a wide range of applications ranging from protein Engineering to the drug design. Swiss dock software was guide to authors to predict the molecular interactions that may occur between a target protein and a small molecule. After review it was analysed that Swiss dock are organised for UV-VIS spectroscopy, Synthesis, crystal, structures, etc. This article presents Swiss Dock, a web server dedicated to the docking of small molecules on target proteins. It is based on the EADock DSS engine, combined with setup scripts for curating common problems and for preparing both the target protein and the ligand input files. An efficient Ajax/ HTML interface was designed and implemented so that scientists can easily submit dockings and retrieve the predicted complexes. For automated docking tasks, a programmatic SOAP interface has been set up and template programs can be downloaded in Perl, Python and PHP. The web site also provides an access to a database of manually curated complexes, based on the Ligand Protein Database.


Cite this article:
Neha Subhash Patil, Sachin H. Rohane. Organization of Swiss Dock: In study of Computational and Molecular Docking Study. Asian J. Research Chem. 2021; 14(2):145-148. doi: 10.5958/0974-4150.2021.00027.4

Cite(Electronic):
Neha Subhash Patil, Sachin H. Rohane. Organization of Swiss Dock: In study of Computational and Molecular Docking Study. Asian J. Research Chem. 2021; 14(2):145-148. doi: 10.5958/0974-4150.2021.00027.4   Available on: https://ajrconline.org/AbstractView.aspx?PID=2021-14-2-10


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