ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Abdelhakim Benarima, Mohamed Nasreddine Raache, Moulay Rachid Kouadri, Yassine Belaiche, Salah Eddine Laouini

Email(s): benarimaabdelhakim@gmail.com

DOI: 10.52711/0974-4150.2021.00062   

Address: Abdelhakim Benarima1*, Mohamed Nasreddine Raache2, Moulay Rachid Kouadri2, Yassine Belaiche1, Salah Eddine Laouini1
1Department of Process Engineering and Petrochemistry, Faculty of Technology, University of Echahid Hamma Lakhdar, El-Oued, BP 789, El-Oued, 39000, Algeria.
2Process Engineering Laboratory (PEL), Kasdi Merbah University, Ouargla, 30000, Algeria.
*Corresponding Author

Published In:   Volume - 14,      Issue - 5,     Year - 2021


ABSTRACT:
Moringa oleifera is considered one of the most useful plants in the world because it's rich in bioactive substances, which employing on modern medical treatment, also can be used for many fields: pharmaceutical, food and cosmetics purposes. In this study, the response surface methodology (RSM) based on a Box–Behnken design (BBD) was employed to optimize the extraction time (X1: 20–60 min), extraction temperature (X2: 15–45 °C) and solvent-solid ratio (X3: 5–7 ml/g), to obtain a high crude of flavonoids yield from Moringa oleifera Leaves by ultrasonic-assisted extraction technique (UAE). The optimum conditions were an extraction time 23 (min), extraction temperature 44 (°C) and solvent-solid ratio 5.05 (ml/g). Under these conditions, the experimental yield was 72.65 (mg ER/g), well matched with the predicted yield 74.34 (mg ER/g) with the coefficients of determination (R2= 0.9861), thus indicating the suitability of response surface methodology in optimizing the ultrasound-assisted extraction of flavonoids from Moringa oleifera Leaves.


Cite this article:
Abdelhakim Benarima, Mohamed Nasreddine Raache, Moulay Rachid Kouadri, Yassine Belaiche, Salah Eddine Laouini. Optimization of Ultrasonic-Assisted Extraction of Flavonoids from Moringa oleifera Leaves Using Response Surface Methodology. Asian Journal of Research in Chemistry. 2021; 14(5):363-7. doi: 10.52711/0974-4150.2021.00062

Cite(Electronic):
Abdelhakim Benarima, Mohamed Nasreddine Raache, Moulay Rachid Kouadri, Yassine Belaiche, Salah Eddine Laouini. Optimization of Ultrasonic-Assisted Extraction of Flavonoids from Moringa oleifera Leaves Using Response Surface Methodology. Asian Journal of Research in Chemistry. 2021; 14(5):363-7. doi: 10.52711/0974-4150.2021.00062   Available on: https://ajrconline.org/AbstractView.aspx?PID=2021-14-5-11


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