2-Arylamino/arylidinehydrazino-4-(4-methoxyphenyl-2-yl) thiazoles were obtained by the reaction of 1-bromoacetyl-4-methoxyphenyl with various substituted arylthioureas and arylidinethiosemicarbazides in ethanol. Aminogroup of aryl thiazole have been treated with different aromatic aldehydes afford corresponding schiff bases, which on further treated with chloroacetylchloride and mercaptoacetic acid converted to corresponding azetidinones and thiazolidinones. All the compounds were characterized on basis of analytical and spectral data and these compounds were screened for invitro antimicrobial activity.
Cite this article:
Raga Basawaraj, Majid Shabbir. Synthesis and Biological Screening of Some New Series of Aryl Thiazole Derivatives. Asian J. Research Chem. 2(4):Oct.-Dec. 2009 page 440-444.