Devika G.S., M. Sudhakar, J. Venkateshwara Rao
Devika G.S. 1*, M. Sudhakar1, J. Venkateshwara Rao2
1Department of Pharmaceutical Chemistry, Malla Reddy College of Pharmacy, Maissamaguda, Dullapally, Secunderabad -14, Andrapradesh, India.
2Department of Pharmaceutical Chemistry, Sultan Ul Uloom College of Pharmacy, Road No3, Banjara Hills , Secunderabad- 500034, Andra pradesh, India.
Volume - 4,
Issue - 5,
Year - 2011
The working conditions for the high pressure liquid Chromatography method was established for Asprin, Atorvastatin and Clopidogrel and then applied on pharmaceutical dosage forms. A rapid sensitive of Chromarographic separation was accomplished using hypersil BDS C18 (250×4.6 mm, 5µ ) analytical column with mobile phase consisting of, acetonitrile, water (pH 3)and methanol (50:40:10 v/v). The eluent were detected by UV absorbance at 248 nm. The developed method was validated in terms of accuracy, precision, linearity, limit of detection, limit of quantification and solution stability. The proposed method can be used for the estimation of these drugs in combined pharmaceutical dosage forms.
Cite this article:
Devika G.S., M. Sudhakar, J. Venkateshwara Rao. A New Simple RP-HPLC Method for Simultaneous Estimation of Asprin, Atorvastatin and Clopidogrel in Capsule Dosage Form. Asian J. Research Chem. 4(5): May, 2011; Page 795-799.