ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): omsubhra Ghosh, Mithiles Kumar, Satyabrata Jena, David Banji, Subhadip Roy

Email(s): som_subhra_ghosh@yahoo.co.in

DOI: Not Available

Address: Somsubhra Ghosh1*, Mithiles Kumar1, Satyabrata Jena1, Dr. David Banji1, Subhadip Roy2
1Department of Pharmaceutical Analysis and Quality Assurance, Nalanda College of Pharmacy, Cherlapally, Nalgonda, Andhra Pradesh -500081, India.
2Mylan Laboratories Ltd, Hyderabad, Andhra Pradesh, India.
*Corresponding Author

Published In:   Volume - 5,      Issue - 12,     Year - 2012


ABSTRACT:
The present research work discusses the development of UV Spectrophotometric method for the determination of Rilpivirine in bulk and pharmaceutical tablet dosage form. The present method is simple, rapid, accurate, precise and economical when compared to other methods. The absorption maxima of the drug were found to be 282nm for Rilpivirine in methanol solvent system. The method is applied to tablet dosage form it gives best results of accuracy, precision & linearity over a range of 2-8µg/ml for Rilpivirine. The percentage recovery was found to be 101% for Rilpivirine. Results were analysed and validated for various parameters as per ICH guidelines.


Cite this article:
omsubhra Ghosh, Mithiles Kumar, Satyabrata Jena, David Banji, Subhadip Roy. Method Development and Validation of Rilpivirine in bulk and Pharmaceutical Tablet Dosage Form by using UV – Visible Spectrophometric Method. Asian J. Research Chem. 5(12): Dec., 2012; Page 1472-1475.


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