Asian Journal of Research in Chemistry

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0974-4150 (Online)
0974-4169 (Print)


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Synthesis, Characterization of Substituted 3-Cyanopyrroles and Evaluation of Antimicrobial Activity.

Author(s): Pawar Rupali Rajaram, Mohite Shrinivas Krishna

Email(s): pawarrupali75@gmail.com

DOI: Not Available

Address: Pawar Rupali Rajaram*, Mohite Shrinivas Krishna
R.C.P. Kasegaon, Sangli, (Maharashtra) India., India
*Corresponding Author

Published In:   Volume - 6,      Issue - 11,     Year - 2013

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ABSTRACT:
A straightforward simple synthesis of substituted 3-cyanopyrroles using Paal–Knorr method has been accomplished with a satisfactory yield. The Paal–Knorr pyrrole synthesis, which involves the reaction of dicarbonyls with amines, is among the most classical methods of heterocyclic pyrrole ring synthesis. The detailed sequence and the nature of the intermediates that occur in the Paal–Knorr reaction mechanism are not well understood. This method produces pyrroles with multicyclic aromatic amines. A series of substituted 3-cyanopyrrole derivatives were evaluated for anti-inflammatory and antimicrobial activity.


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Cite this article:
Pawar Rupali Rajaram, Mohite Shrinivas Krishna. Synthesis, Characterization of Substituted 3-Cyanopyrroles and Evaluation of Antimicrobial Activity. Asian J. Research Chem. 6(11): November 2013; Page 1040-1043.

Cite(Electronic):
Pawar Rupali Rajaram, Mohite Shrinivas Krishna. Synthesis, Characterization of Substituted 3-Cyanopyrroles and Evaluation of Antimicrobial Activity. Asian J. Research Chem. 6(11): November 2013; Page 1040-1043.   Available on: https://ajrconline.org/AbstractView.aspx?PID=2013-6-11-11


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Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

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Asian Journal of Research in Chemistry (AJRC) (ISSN: print-0974-4169, Online-0974-4150) is an international, peer-reviewed journal devoted to pure and applied chemistry. AJRC publishes Original Research Articles, Short Communications, Review Articles in all aspects of chemistry. Topics covered including the traditional areas of analytical, inorganic, organic, biochemistry, forensic, physical-theoretical chemistry as well as newer interdisciplinary areas such as agriculture, materials science, computational, medicine, spectroscopy, polymers, supramolecular, surface, chemical physics, biological, medicinal/ drugs, environmental and pharmaceutical chemistry.
The journal is published quarterly every year in last week of March, June, September and December. From January 2011, is monthly and shall be published every year in last week of Month.    
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