ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Pawar Rupali Rajaram, Mohite Shrinivas Krishna

Email(s): pawarrupali75@gmail.com

DOI: Not Available

Address: Pawar Rupali Rajaram*, Mohite Shrinivas Krishna
R.C.P. Kasegaon, Sangli, (Maharashtra) India., India
*Corresponding Author

Published In:   Volume - 6,      Issue - 11,     Year - 2013


ABSTRACT:
A straightforward simple synthesis of substituted 3-cyanopyrroles using Paal–Knorr method has been accomplished with a satisfactory yield. The Paal–Knorr pyrrole synthesis, which involves the reaction of dicarbonyls with amines, is among the most classical methods of heterocyclic pyrrole ring synthesis. The detailed sequence and the nature of the intermediates that occur in the Paal–Knorr reaction mechanism are not well understood. This method produces pyrroles with multicyclic aromatic amines. A series of substituted 3-cyanopyrrole derivatives were evaluated for anti-inflammatory and antimicrobial activity.


Cite this article:
Pawar Rupali Rajaram, Mohite Shrinivas Krishna. Synthesis, Characterization of Substituted 3-Cyanopyrroles and Evaluation of Antimicrobial Activity. Asian J. Research Chem. 6(11): November 2013; Page 1040-1043.


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