Title compounds of 1,3,4-oxadiazoles derivatives by the ring closure reaction of m-fluorobenzoic acid hydrazide with an aromatic acid and alumina in presence of POCl3 under microwave irradiation. All the newly synthesized compounds were screened for their antibacterial activity against Gram-positive bacteria namely staphylococcus aureus, Bacillus subtilis and Gram-negative bacteria namely, Escherichia coli and Pseudomonas aeruginosa. All the synthesized compounds were also tested for their antifungal activity against fungi namely, Candida albicans.
Cite this article:
Ajay N. Mehta, Jayraj Yadav, K.R. Desai. Eco-Friendly Synthesis of Novel Fluorine Containing 1,3,4-Oxadiazoles as Antibacterial and Antifungal Agents. Asian J. Research Chem. 6(5): May 2013; Page 486-489.