ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Dipali Uthale, S. K. Mohite

Email(s): deep9225@yahoo.in

DOI: Not Available

Address: Dipali Uthale*, Dr. S. K. Mohite
Rajarambapu College of Pharmacy, Kasegaon-415409, Maharashtra, India.
*Corresponding Author

Published In:   Volume - 7,      Issue - 1,     Year - 2014


ABSTRACT:
An efficient synthesis of different novel 4,5–diphenyl pyrrole derivatives by the paal- knorr condensation has been accomplished using substituted aniline and 1,4 – diketone. The synthesized compounds were confirmed through spectral characterization using IR, 1H NMR. The pyrrole derivatives examined for their in vitro antimicrobial activity and in vivo anti- inflammatory. Result indicated that these compounds showed promising anti microbial and anti- inflammatory activity in comparison to amoxicillin and ibuprofen (the standard antimicrobial and anti–inflammatory drugs). Tolmetin (Rumatol) and Ketorolac (Ketolac), nonsteroidal anti-inflammatory drugs (NSAIDs) containing pyrrole ring, are nonselective inhibitors of cyclooxygenase 1 and 2 enzymes that led to decrease prostaglandin synthesis.


Cite this article:
Dipali Uthale, S. K. Mohite. Synthesis and Anti-Inflammatory Activity of Some 4,5 Diphenyl Pyrrole Derivatives. Asian J. Research Chem 7(1): January 2014; Page 58-61.


Recomonded Articles:

Author(s): Gullipilli Sandhya, R. Ravichandra Babu

DOI: 10.5958/0974-4150.2018.00115.3         Access: Open Access Read More

Author(s): Mukesh K. Nagar, Karishma R. Waghmare, P.N. Dhabale, Pradeep D. Chanekar, Suresh Bhatia

DOI:         Access: Open Access Read More

Author(s): Pankaj Baboo, Girendra Gautam, S.K. Gupta

DOI: 10.5958/0974-4150.2017.00039.6         Access: Open Access Read More

Author(s): Kadhiravansivasamy, S. Sivajiganesan, T. Periyathambi, V. Nandhakumar, M. Pugazhenthi

DOI: 10.5958/0974-4150.2017.00016.5         Access: Open Access Read More

Author(s): Nandkishor G. Telkapalliwar, Dhanashri M. Borikar, Vidyadhar M. Shivankar

DOI: 10.5958/0974-4150.2017.00049.9         Access: Open Access Read More

Author(s): Anilkumar Kodge, Arunkumar lagashetty

DOI: 10.5958/0974-4150.2017.00023.2         Access: Open Access Read More

Author(s): SR Pattan, NS Dighe, SA Nirmal, AN Merekar, RB Laware, HV Shinde, DS Musmade

DOI:         Access: Open Access Read More

Author(s): Mukund Nagarnaik, Arun Sarjoshi, Ajay Bodkhe, Bhupendra Khanal, Mayuri Pise, Girish Pandya

DOI: 10.5958/0974-4150.2015.00102.9         Access: Open Access Read More

Author(s): K. Kishore Kumar, R.S.K. Sharma, P. Chanti Babu, M. Sreenivasa Rao, K. Durga Prasadu, D. Ravi Kumar

DOI: 10.5958/0974-4150.2017.00067.0         Access: Open Access Read More

Author(s): Anshul Sinha, A. K. Meena, P. Panda, Bhavana Srivastava, M. D. Gupta, M. M. Padhi

DOI:         Access: Open Access Read More

Author(s): Hunasnalkar Shivraj G, Shaikh Gazi, Patil SM, Surwase Ulhas S

DOI:         Access: Open Access Read More

Author(s): Toyaj Shukla, Shishir Malviya, Abhishek Kumar, Shekhar Srivastava

DOI: 10.5958/0974-4150.2017.00061.X         Access: Open Access Read More

Author(s): Alok Singh Thakur, Parmanand Verma, Anish Chandy

DOI:         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags