ABSTRACT:
1-Oxo-1H-isochromene-3-carbaldehyde (1) reacts with Indan-1-one (2) to offer 4-(1-Oxo-indan-2-ylidenemethyl)-isochromen-1-one (3) which on reaction with liquid ammonia produces 3-(1-Oxo-indan-2-ylmethyl)-isochromen-1-one (4). Compound 4 is reduced with LDA to 3-(2-Methyl-1-oxo-indan-2-ylmethyl)-isochromen-1-one (5). The structures of the compounds are confirmed by spectral data.
Cite this article:
S. Shiva Rama Krishna and R. Sreenivasulu. Methodology Study and a Practical, Cost Efficient Synthesis of a 3-(2-Methyl-1-oxo-indan-2-ylmethyl)-isochromen-1-one. Asian J. Research Chem. 2018; 11(3):585-587. doi: 10.5958/0974-4150.2018.00104.9
Cite(Electronic):
S. Shiva Rama Krishna and R. Sreenivasulu. Methodology Study and a Practical, Cost Efficient Synthesis of a 3-(2-Methyl-1-oxo-indan-2-ylmethyl)-isochromen-1-one. Asian J. Research Chem. 2018; 11(3):585-587. doi: 10.5958/0974-4150.2018.00104.9 Available on: https://ajrconline.org/AbstractView.aspx?PID=2018-11-3-13