Asian Journal of Research in Chemistry

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0974-4150 (Online)
0974-4169 (Print)


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Methodology Study and a Practical, Cost Efficient Synthesis of a 3-(2-Methyl-1-oxo-indan-2-ylmethyl)-isochromen-1-one

Author(s): S. Shiva Rama Krishna and R. Sreenivasulu

Email(s): shivarama_samala@rediffmail.com

DOI: 10.5958/0974-4150.2018.00104.9   

Address: S. Shiva Rama Krishna*1 and R. Sreenivasulu2
*1Research Scholar, Mewar University, Rajasthan, India
2Research Supervisor, Mewar University, Rajasthan, India
*Corresponding Author

Published In:   Volume - 11,      Issue - 3,     Year - 2018

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ABSTRACT:
1-Oxo-1H-isochromene-3-carbaldehyde (1) reacts with Indan-1-one (2) to offer 4-(1-Oxo-indan-2-ylidenemethyl)-isochromen-1-one (3) which on reaction with liquid ammonia produces 3-(1-Oxo-indan-2-ylmethyl)-isochromen-1-one (4). Compound 4 is reduced with LDA to 3-(2-Methyl-1-oxo-indan-2-ylmethyl)-isochromen-1-one (5). The structures of the compounds are confirmed by spectral data.


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Cite this article:
S. Shiva Rama Krishna and R. Sreenivasulu. Methodology Study and a Practical, Cost Efficient Synthesis of a 3-(2-Methyl-1-oxo-indan-2-ylmethyl)-isochromen-1-one. Asian J. Research Chem. 2018; 11(3):585-587. doi: 10.5958/0974-4150.2018.00104.9

Cite(Electronic):
S. Shiva Rama Krishna and R. Sreenivasulu. Methodology Study and a Practical, Cost Efficient Synthesis of a 3-(2-Methyl-1-oxo-indan-2-ylmethyl)-isochromen-1-one. Asian J. Research Chem. 2018; 11(3):585-587. doi: 10.5958/0974-4150.2018.00104.9   Available on: https://ajrconline.org/AbstractView.aspx?PID=2018-11-3-13


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Asian Journal of Research in Chemistry (AJRC) (ISSN: print-0974-4169, Online-0974-4150) is an international, peer-reviewed journal devoted to pure and applied chemistry. AJRC publishes Original Research Articles, Short Communications, Review Articles in all aspects of chemistry. Topics covered including the traditional areas of analytical, inorganic, organic, biochemistry, forensic, physical-theoretical chemistry as well as newer interdisciplinary areas such as agriculture, materials science, computational, medicine, spectroscopy, polymers, supramolecular, surface, chemical physics, biological, medicinal/ drugs, environmental and pharmaceutical chemistry.
The journal is published quarterly every year in last week of March, June, September and December. From January 2011, is monthly and shall be published every year in last week of Month.    
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