ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Rele Rajan V., Tiwatane Prathamesh P.

Email(s): drvinraj@gmail.com

DOI: 10.5958/0974-4150.2020.00036.X   

Address: Rele Rajan V.*, Tiwatane Prathamesh P.
Central Research Laboratory, D.G. Ruparel College Mahim, Mumbai 400 016.
*Corresponding Author

Published In:   Volume - 13,      Issue - 3,     Year - 2020


ABSTRACT:
A simple precise, rapid accurate and sensitive titration method was developed for quantitative determination of isoxsuprine hydrochloride in pharmaceutical dosage form. The titration was carried out using standardized 0.1 N sodium hydroxide solution. The proposed method was found to be precise with % RSD <1 (n = 6). The method showed strict linearity (r2 > 0.99) between 10 % to 50 % of 500 mg of drug, substance weight. The percentage recovery of isoxsuprine hydrochloride in the optimized method was 99.02 % to 99.84 %. The method is also found to be rugged when checked by different analysts and using different lots of reagents and different laboratories.


Cite this article:
Rele Rajan V., Tiwatane Prathamesh P. A Validated Simple Titrimetric Method for the Quantitative determination of Isoxsuprine hydrochloride from Pharmaceutical dosages. Asian J. Research Chem. 2020; 13(3):187-189. doi: 10.5958/0974-4150.2020.00036.X


REFERENCES
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