Author(s):
Chetehouna Sara, Atoussi Ouidad, Boulaares Islam, Guemari Imane Yousra, Derouiche Samir
Email(s):
Email ID Not Available
DOI:
10.5958/0974-4150.2020.00086.3 
Address:
Chetehouna Sara1, Atoussi Ouidad1, Boulaares Islam1, Guemari Imane Yousra1, Derouiche Samir1,2
1Department of Cellular and Molecular Biology, Faculty of Natural and Life Sciences, University of Echahid Hamma Lakhdar El Oued, El Oued 39000, Algeria.
2Laboratory of Biodiversity and Application of Biotechnology in the Agricultural Field, University of El Oued, El-Oued 39000, Algeria.
*Corresponding Author
Published In:
Volume - 13,
Issue - 6,
Year - 2020
ABSTRACT:
Our study aimed to evaluate the effect of cigarette consumption on lipid profile, blood pressure and biochemical biomarkers of cardiovascular diseases in smoker’s men. The experimentation is carried out on 22 voluntary individuals were divided into two groups; the first group of healthy individuals (controls) and the second group was tobacco smokers. All the volunteers were subjected to estimate the blood pressure, lipid profile, biochemical and hematological parameters. The finding results showed that there was a significant increase (P<0.001) of systolic blood pressure in smokers when we compare to the control subjects. Also, the level of TC, TG, VLDL-c, LDL-c and Atherogenic index (AI) were highly significant raised (P<0.01), while the HDL-c level is significantly decreased (P<0.001) for smokers group compared to the controls one. However, the biochemical parameters didn’t change. The hematological results demonstrated that there was a significant decrease in RBC (p<0.01) and PLT (p<0.001) levels while a significant increase in MCV (p<0.05) level in smokers compared to the controls. Also, a significant raise in WBC (p<0.05) and Lym (p<0.001) levels were noticed in smokers group compered to controls one. As conclusion our study reveals that the tobacco consumption in cigarette form may be induce the sever alteration in lipid profile which cause the change in blood pressure that increase the cardiovascular risk for this population, Additionally, the cigarette smoke may be lead to remarkable change in blood constituents and appearance of inflammation status in the body.
Cite this article:
Chetehouna Sara, Atoussi Ouidad, Boulaares Islam, Guemari Imane Yousra, Derouiche Samir. The effect of Chronic Tobacco smoking on Atherogenic index and Cardiovascular diseases risk in El-Oued (Algeria) Men. Asian J. Research Chem. 2020; 13(6):489-493. doi: 10.5958/0974-4150.2020.00086.3
Cite(Electronic):
Chetehouna Sara, Atoussi Ouidad, Boulaares Islam, Guemari Imane Yousra, Derouiche Samir. The effect of Chronic Tobacco smoking on Atherogenic index and Cardiovascular diseases risk in El-Oued (Algeria) Men. Asian J. Research Chem. 2020; 13(6):489-493. doi: 10.5958/0974-4150.2020.00086.3 Available on: https://ajrconline.org/AbstractView.aspx?PID=2020-13-6-13
REFERENCES:
1. Patil SS, Patil SN, Somade PM. Comparative study of Pulmonary Function tests in Tobacco chewers and non-tobacco chewers. Indian Journal of Basic and Applied Medical Research; 2018; 8 (1): 208 – 214.
2. Bakdash A. Shammah (Smokeless Tobacco) and Public Health. Asian Pac J Cancer Prev, 2017; 18 (5): 1183-1190. Doi:10.22034/APJCP.2017.18.5.1183
3. Ahmed QR, Gupta N, Goyal S, Ansari S J. Comparative study on lipid profile in tobacco chewers and nontobacco chewers. National Journal of Physiology, Pharmacy and Pharmacology, 2015; 5 (2): 142 – 144.
4. Radha A R, Anjana S B. Comparison of Lipid Profile Levels in Tobacco Chewers with and without Leukoplakia–A Hospital Based Study. Annals of Medical and Health Sciences Research, 2017; 7: 341-345.
5. Kwamena S D, Bright O A. Understanding tobacco use and socioeconomic inequalities among men in Ghana, and Lesotho. Dickson and Ahinkorah Archives of Public Health, 2017; 75 (30): 1-8.
6. Derouiche S, Degachi O, Gharbi K. Phytochemistry analysis and modulatory activity of Portulacae oleracea and Aquilaria malaccensis extracts against High-fructose and high-fat diet induced immune cells alteration and heart lipid peroxidation in Rats. International Research Journal of Biological Sciences. 2019; 8(4): 6-11.
7. Amit D S, Shylaja T V, Asmabi M, Zahoorunissa D. Study of Lipid Profile among Healthy Smokers and Non Smokers. International Journal of Biotechnology and Biochemistry, 2017; 13 (1): 87-94.
8. Zafeiridou M, Hopkinson N S, Voulvoulis N. Cigarette smoking an assessment of tobacco’s global environmental footprint across its entire supply chain and policy strategies to reduce it. Geneva World Health Organization, 2018; 1-48.
9. Padmavathi P, Raghu PS, Reddy VD, Bulle S, Marthadu SB, Maturu P, Varadacharyulu NC. Chronic cigarette smoking-induced oxidative/nitrosative stress in human erythrocytes and platelets. Mol Cell Toxicol, 2018; 14:27-34. Doi: 10.1007/s13273-018-0004-6.
10. Derouiche S, Abbas K, Djermoune M. Changes in metabolism of Zinc and carbohydrate and testis oxidative stress of diabetic rats fed zinc-over dose diet. Int J Biol Med Res. 2017; 8(3):6041-6045.
11. Joshi N, Shah, Mehta HB, Gokhle PA. Comparative study of lipid profile on healthy smoker and non smokers. International Journal of Medical Science and Public Health, 2013; 2:622-626.
12. Samir D, Dalal D, Noura A. Effect of routine iron supplementation on copper level and oxidative stress status in pregnant women. Asian Pac J Reprod 2020; 9(2): 64-69.
13. Croizet J, Perriot F, Merson B, Aublet C. Sevrage tabagique des fumeurs agés Etude rétrospective chez 181 fumeurs agés pris en charge en centre de tabacologie. Revue des Maladies Respiratoires, 2016 ; 33 :241-247.
14. Friedewald WT, Levy RI, Fredrickson DS. Estimation of concentration of low-density lipoprotein cholesterol in plasma without use of ultracentrifuge. Clin Chem, 1972; 18: 499-502.
15. Gomina M, Ngobi GY, Akpona SA. Profil des lipides seriques des sujets adultes beninois consommateurs habituels de tabac. European Scientific Journal, 2013; 9(30): 125– 140.
16. Bauer M, Fink B, Thürmann L, Eszlinger M, Herberth G, Lehmann I. Tobacco smoking differently influences cell types of the innate and adaptive immune system—indications from CpG site methylation. Clinical Epigenetics, 2016; 8(83). Doi: 10.1186/s13148-016-0249-7
17. Srinivasa RCH, Emmanuel SY. The Effect of Chronic Tobacco Smoking and Chewing on the Lipid Profile. Journal of Clinical and Diagnostic Research, 2013; 7(1): 31-34.
18. Haragopal R, Aruna BMK. Effects of Tobacco Chewing on Serum Lipid Profile in South Indian Population. International Journal of Scientific Study, 2016; 4(4):9-11.
19. Salman S, Azmat R, Sangeeta S, Deepak P, Shadab K. Assessment of Cardiovascular Risks of Tobacco Chewers by Comparing it with Normal Human Beings. National Journal of Physiology, Pharmacy and Pharmacology, 2014; 4(1): 76 – 79.
20. Judith J. Prochaska and Neal L. Benowitz. Current advances in research in treatment and recovery: Nicotine addiction. Science advances, 2019; 5: 9763.
21. Elhashimi EH, Gabra HM. , Abdalla ZA. , Ali AE. . Effect of Cigarette Smoking on Lipid Profile In Male at Collage of Police and Low Khartoum, Sudan. Asian Journal of Biomedical and Pharmaceutical Sciences, 2013; 3(26):28-31.
22. Zulkefli B. Sanip, BSc, Muhammad Z.B. Suhaimi, BSc, Che N. Man, MSc, Aida H.B.G. Rasool, PhD and Harmy B.M. Yusoff, MMed. Relationship between hair nicotine levels with blood pressure, body composition, lipid profile and leptin among healthy male smokers in Kelantan. Journal of Taibah University Medical Sciences, 2016; 11(1): 50-55. Doi: 10.1016/j.jtumed.2015.11.007
23. Deepa S. Effect of Cigarette Smoking on Serum Lipid Profile in Male Population of Udaipur. Biochem Anal Biochem, 2016; 5(3), 1000283. DOI: 10.4172/2161-1009.1000283
24. Ramachandran M, Chinnasamy R, Ponniah T. Lipid and lipoprotein profiles among middleaged male smokers: a study from southern India. Tobacco Induced Diseases,2010; 8(11): 1-5.
25. Derouiche S, Kechrid Z. Influence of calcium supplements on zinc status, carbohydrate metabolism and the liver activity of detoxifying glutathione enzymatic system in alloxan induced diabetic rats. J Exp Biol Agr Sci. 2013;1(6): 424-429.
26. Ayu A, Ameh E A. Atherogenic indices and smoking habits in cigarette smokers. Environmental Disease, 2018; 3(2): 38-44.
27. Kjell A. Smokeless Tobacco and Cardiovascular Disease. Progress in Cardiovascular Diseases, 2003; 45 (5): 383-394.
28. Feifei Q, Ping F, Golay DN, Huazhen L, Chun-Ling L, Wanlin Y, Zhenhua D. Effects of Cigarette Smoking on Transplant Survival: Extending or Shortening It?. Frontiers in Immunology, 2017; 8. Doi:10.3389/fimmu.2017.00127
29. Dr Devendra Kumar, DR. B.K.Binawara, Mr. Poona Ram Beniwal, Mrs Pooja Sharma. Effect of Chewing Tobacco on Hematological Parameters in Bikaner City Population. JMSCR, 2017; 5(2): 17721-17727. Doi: 10.18535/jmscr/v5i2.87.
30. Derouiche S, Rezzag-mohcen OS, Serouti A. Triazinone herbicide metribuzin induced acute liver injury: A study of animal model. J Acute Dis 2018; 7(4): 152-157. doi:10.4103/2221-6189.241016.
31. Feifei Q, Chun-Ling L, Huazhen L, Yu-Qun Z, Shaozhen H, Song H, Xiaoping L, Zhenhua D. Impacts of cigarette smoking on immune responsiveness: Up and down or upside down? Oncotarget, 2017; 8(1): 268-284.
32. Sharif S, Farasat T, Nargis F, Farooq A, Naz . Effect of Nicotine on Hematology, Lipid Profile and Liver Enzymes in Adult Male Mice (Mus Musculus). Advances in Animal and Veterinary Sciences, 2014; 2 (4): 222 – 225. Doi: 10.14737/journal.aavs/ 2014/2.4. 222.225
33. Atoussi N, Guediri S, Derouiche S. Changes in Haematological, Biochemical and Serum Electrolytes Markers in Women Breast Cancer Patients. Scholars Journal of Research in Agriculture and Biology. 2018, 3(2): 73-177.
34. Acik DY, Suyani E, Aygun B, Bankir M. The Effect of Smoking on Hematological Parameters. Ulutas Med J2020; 6(1):9-14. Doi :10.5455/umj.20200209092535.
35. Bashir BA, Gibreel MO, Abdalatif HM, Mohamed MA, Ahmed EA, Mohamed MS and Hamid KA. Impact of Tobacco Cigarette Smoking on Hematologic parameters among male Subjects in Port Sudan Ahlia College, Sudan. Scholars Journal of Applied Medical Sciences, 2016; 4(4A):1124-1128.
36. Romsha S, Kalpana S. Protective activity of Guduchi and green tea extract on nicotine-induced toxicity in mice. The Pharma Innovation Journal, 2019; 8(1): 650-656.