ABSTRACT:
Momordica cymbalaria is a rare species that belongs to the family Cucurbitacae which is commonly found in the open field of the Lunguda people of Adamawa State, Nigeria. The plant’s root is used by the locals as substitute for soap and detergents due to its high saponin contents. The leaves are consumed by the locals as vegetable in soup preparation. Several species of Momordica have proven medicinal uses and are safe when taken in control dose. This research is aimed at revealing the phytochemical constituents of Momodica cymbalaria and relating same to its usages by the locals. The phytoconstituents of the aqueous and chloroform extracts of the leaf and root were determined. The results show that Saponin, Alkaloids, Carbohydrates, Cardiac glycosides and Balsam are presence in both the leaf and plant extract while Glycoside, Anthraquinones, Cardenolides and Phlobatannins are not presence in the plant parts. Phenols, Terpenoids, Flavonoids are identified in the leaf aqueous extract of the plant but absence in the same root solution. The chloroform extracts show the presence of steroids in the roots part and absence in the leaf. The plant has potential for use in Pharmaceutical, Cosmetics and Agrochemical industries.
Cite this article:
Musa Runde. Determination of Phyto-Constituents of Leaves and Tuber-like Roots of Momordica cymbalaria (Bworhauyala) Grown in Admawa State, Nigeria. Asian Journal of Research in Chemistry. 2023; 16(5):344-8. doi: 10.52711/0974-4150.2023.00055
Cite(Electronic):
Musa Runde. Determination of Phyto-Constituents of Leaves and Tuber-like Roots of Momordica cymbalaria (Bworhauyala) Grown in Admawa State, Nigeria. Asian Journal of Research in Chemistry. 2023; 16(5):344-8. doi: 10.52711/0974-4150.2023.00055 Available on: https://ajrconline.org/AbstractView.aspx?PID=2023-16-5-5
REFERENCE:
1. Chipttapur R. Momordica Cymbalaria A Nutritious Underutilized Vegetable Taxonomy, Nutritional, Medicinal, Propagation, Hybridization and Cytological Aspects. International Journal of Agricultural Science and Research. 2015; 5(4), 255-262
2. Pereira C.A.J., OliveiraL.L.S., Coaglio A.L., Santos F.S.O., Cezar R.S.M., Mendes T., Oliveira F.L.P., Conzensa G and Lima W.S. Anti-helminthic activity of Momordica charantia L. Against Fasciola hepatica eggs after twelve days of incubation in vitro. Veterinary Parasitology. 2016; 228160–166
3. Kumar S.N. and Madhurambal G. Cucurbitacin Glycosides from the fruits of Citrullus colocynthis (L). Research J. Pharmacognosy and Phytochemistry. 2010; 2(3): 200-202.
4. Nagarani G., Abirami A. and Siddhuraju P. A comparative study on antioxidant potentials, inhibitory activities against key enzymes related to metabolic syndrome, and anti-inflammatory activity of leaf extract from different Momordica species. Food Science and Wellness. 2014; 3(1): 36-46
5. Mituiassu M.P., Serdeiro M.T., Vieira R.R..B.T., Oliveira L.S. and Maleck M. Momordica charantia L. Extracts against Aedesaegypti larvae. Brazilian Journal of Biology. 2022; 82: e236498 |https://doi.org/10.1590/1519-6984.236498
6. Kumar K.P.S. and Bhowmik D. Traditional Medicinal Uses and Therapeutic Benefits of Momordica Charantia Linn. International Journal of Pharmaceutical Science Research and Review. 2010; 4(3), Article 004
7. Nikhat F., Satyanarayana D., Shastri C.S., Moid A., Thouheed A.. Investigation of Phytoconstituents, from Momordica charantia Linn Roots and Screening them, for Anti-Hyperglycemic Activity. Asian J. Research Chem. 2014; 7(3): 256-261
8. Sachin U Rakesh, Priyanka R Patil, Vijay R Salunkhe. Momordica Charantia Linn – A Comprehensive Review. Research J. Pharmacognosy and Phytochemistry. 2009; 1(2): 98-102.
9. Jeyabaskar Suganya, Mahendran Radha, Sharanya Manoharan, Vinoba. V, Astral Francis. Virtual Screening and Analysis of Bioactive Compounds of Momordica charantia against Diabetes using Computational Approaches. Research J. Pharm. and Tech. 2017; 10(10):3353-3360.
10. Sugashini Settu, Sathiavelu Arunachalam. Comparison of Phytochemical analysis and In vitro Pharmacological activities of most commonly available medicinal plants belonging to the Cucurbitaceae family. Research J. Pharm. and Tech. 2019; 12(4):1541-1546.
11. Patil N.S., Patil K.B., Patil M.R. and Ahirrao R.A. Antimitotic Activity of Fruits of Momordica dioica by using Allium cepa Root Tip Assay. Asian J. Pharm. Res. 2018; 8(4): 221-224.
12. Thakur G.S., Bag M., Sanodiya B.S, Bhadauriya P. Debnath M., Prasad G.B.K.S and Bisen P.S. Momordica balsamina: A Medicinal and Neutraceutical Plant for Health Care Management. Current Pharmaceutical Biotechnology. 2009; 7(10), 667-680
13. Nikhat F., Satyanarayana D., Shastri C.S., Rajni S., Sheikh A.S. The Phytochemicals explored from the roots of Syzygium cuminni (L) skeel assessed for Anti-hyperglycemic activity. Asian J. Research Chem. 2013; 6(10): 920-925
14. Odebiyi, A. and Sofowora A.E. Phytochemical screening of Nigerian medicinal plants part III Lloydia. 1990; 41: 234-246
15. Fadeyi, N.G., Adeoye A.E and Olowokodejo, J.D. Epidermal and phytochemical studies with genus of Boerhavia (Nyetanginaceae) crude Drug Res. 1989; 29: 178-184
16. Kubmarawa, D., Ajoku, G.A., Enwerem N.M. and Okorie D.A. Preliminary Phytochemical and Antimicrobial screening of 50 Medicinal plants from Nigeria. African Journal of Biotechnology. 2007; 6(14): 1690-1696
17. Ahamad J., Amin S. and Mir S.R. Momordica charantia Linn. (Cucurbitaceae): Review on Phytochemistry and Pharmacology. Research Journal of Phytochemistry. 2017; 11: 53-65.
18. Sulaiman A. and Yakubu M. Chemical Composition of Momordica Charantia Leaves. Proceedings of 105th The IRES International Conference, Putrajaya, Malaysia. 2018; 4th -5th March,
19. Ramalhete C. Bruno M. F. Gonc¸ alves. Filipa Barbosa. Noe´lia Duarte. Maria-Jose´ U. Ferreira Custódio D.L. and Veiga-Junior V.F. True and common balsams. Brazilian Journal of Pharmacognosy. 2012; 22(6): 1372-1383
20. Supraja P, Basha T, Nagaraju C., Kiranmayee P. and Usha. R. Identification of an Alkaloid Momordicin from Fruits of Momordica Charantia L. International Journal of Scientific and Engineering Research. 2015; 6(2): 168-172
21. Singh J., Cumming E., Manoharam G., Kalsz H. and Adeghate E. Medicinal Chemistry of the Anti-Diabetic Effects of Momordica Charantia: Active Constituents and Modes of Actions. Open Medicinal and Chemical Journal. 2001; 5: 70-77 doi: 10.2174/1874104501105010070
22. Taylor L. Herbal Secrets of the Rainforest. 2nd edition. Sage Press, Austin Texas USA 2002
23. Agrawal M.R, Aher A.N., and Pal S.C. Isolation, Characterization of Phytoconstituents from petroleum ether extract of Momordica balsamina fruits and its quantitative analysis by HPTLC. Res. J. Pharmacognosy and Phytochem. 2020; 12(3):156-161.
24. Muronga M., Quispe C., Tshikhudo P.P., Msagati T.A., Mudau F.M., Kamal R.M. and Sharifi-Rad J. Three Selected Edible Crops of the Genus Momordica as Potential Sources of Phytochemicals: Biochemical, Nutritional, and Medicinal Values. Frontiers in Phamacology. 2021; 12: doi: 10.3389/fphar.2021.625546
25. Heinrich M., Mah J. and Amirkia V. Alkaloids Used as Medicines: Structural Phytochemistry Meets Biodiversity—An Update and Forward Look. Molecules. 2021; 26(7); 1836
26. Ul-Ain Q., Khan H, Mubarak M.S. and Pervaiz A. Plant Alkaloids as Antiplatelet Agent: Drugs of the Future in the Light of Recent Developments. Frontiers in Pharmacology. 2016; https://doi.org/10.3389/fphar.2016.00292
27. Victor K. 21-Heath Effects of alkaloids from African Medicinal plants. Toxxicological Survey of African Medicinal Plants. 2014; 611-633
28. Qureshi Md. Shamim, Patel Jitendra, Venkateshwar Reddy A, Syed Safiullah, P Mohapatra. Phytochemicals and Pharmacological Activities of Moringa oleifera Lam. Research J. Pharmacology and Pharmacodynamics. 2010; 2(2):183-186.
29. Shi J., Arunasalam K., Yeung D., Kakuda Y., Mittal G. and Jiang Y. Saponins from edible legumes: chemistry, processing, and health benefits. Journal of Medicine and Food. Spring. 2004; 7(1): 67-78. doi: 10.1089/109662004322984734. PMID: 15117556.
30. Zaman K., Adibah M. and Azzreena M.A. Plant toxins: alkaloids and their toxicities. GSC Biological and Pharmaceutical Sciences. 2019; 06(02): 021–029
31. Chuck K. Fishing with poison. Available online @ https://www.primitiveways.com/fish_poison.html. 2003; Visited on 2nd October 2022
32. Johnson T.O and Olatoye R.S. Phytochemical and Antimicrobial Screening of Aqueous and Ethanolic Extracts of Annona senegalenses Leaf. Journal of Medicine in the Tropics. 2012; 14(2): https://www.ajol.info/index.php/jmt/article/view/80363
33. Jia S., Shen M., Zhang F. and Xie J. Resent Advances in Momordica charantia: Functional compounds and Biological Activities. International Journal of Science. 2017; 18(12): 2555 doi: 10.3390/ijms18122555
34. Ujjwala Supe, Prarthna Daniel. HPLC Method for Analysis of Bioactive Compound from Momordica charantia. Research J. Pharm. and Tech. 2015; 8(12): 1649-1652.