ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Amit Rathi, Dinesh Dhamecha, Saifee Maria, Mohd Hassan G Dehghan

Email(s): amit.pharmaceutics@gmail.com

DOI: Not Available

Address: Amit Rathi*, Dinesh Dhamecha, Saifee Maria and Mohd Hassan G Dehghan
Y.B.Chavan College of Pharmacy ,Dr. Rafiq Zakaria Campus, Maulana Azad Education Trust, Rauza Bagh , Aurangabad (MS) India. 431001
*Corresponding Author

Published In:   Volume - 2,      Issue - 2,     Year - 2009


ABSTRACT:
The present research work discusses the development of a UV estimation method for Idebenone. Simple, accurate, cost efficient and reproducible spectrophotometric method has been developed for the estimation of Idebenone in bulk and pharmaceutical dosage form. UV spectrophotometric method, which is based on measurement at maximum wavelength (?max) 282nm. The percentage recovery of Idebenone ranged from 99.68 to 99.82% in pharmaceutical dosage form. Beers law was obeyed in the concentration range of 4-20µg/ml having line equation y = 0.0485x - 0.0239 with correlation coefficient of 0.9978. Results of the analysis were validated statistically and by recovery study.


Cite this article:
Amit Rathi, Dinesh Dhamecha, Saifee Maria, Mohd Hassan G Dehghan. Development of UV Spectrophotometric method of Idebenone in Bulk and Pharmaceutical Formulation. Asian J. Research Chem. 2(2): April.-June, 2009 page 168-170.


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