ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): HusnainFathima, Mahboob Pasha, Mohamed Khaleel

Email(s): husnainfathima35@gmail.com

DOI: 10.52711/0974-4150.2023.00033   

Address: HusnainFathima, Mahboob Pasha, Mohamed Khaleel
Department of Pharmaceutical Chemistry, MMU College of Pharmacy, Ramanagar-562159 Karnataka, India.
*Corresponding Author

Published In:   Volume - 16,      Issue - 3,     Year - 2023


ABSTRACT:
A simple, sensitive, accurate, rapid and economical Spectrophotometric method was developed for estimation and validation of Finerenone in pure drug and tablet dosage form. The absorbance was measured at 239.8nm using Ethanol as solvent system. It obeyed Beer’s law at the concentration range of 2-14µg/ml with coefficient of correlation (r2) of 0.997. Limit of detection (LOD) was found to be 1.220µg/ml and Limit of quantitation (LOQ) was found to be 5.220µg/ml. The proposed analytical method was validated according to ICH guidelines, yielded good results concerning range, linearity, precision, accuracy, robustness and ruggedness.


Cite this article:
HusnainFathima, Mahboob Pasha, Mohamed Khaleel. Estimation and Validation of Finerenone in Dosage Form and in Bulk Drug by Spectrophotometric Method. Asian Journal of Research in Chemistry 2023; 16(3):211-5. doi: 10.52711/0974-4150.2023.00033

Cite(Electronic):
HusnainFathima, Mahboob Pasha, Mohamed Khaleel. Estimation and Validation of Finerenone in Dosage Form and in Bulk Drug by Spectrophotometric Method. Asian Journal of Research in Chemistry 2023; 16(3):211-5. doi: 10.52711/0974-4150.2023.00033   Available on: https://ajrconline.org/AbstractView.aspx?PID=2023-16-3-3


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