ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): P Nagaraju, D Narendra, P Jitendra Kumar, VDN Srinivas, SVN Padma

Email(s): raju_pharma35@rediffmail.com

DOI: Not Available

Address: P Nagaraju*, D Narendra, P Jitendra Kumar, VDN Srinivas and SVN Padma
Hindu College of Pharmacy, Amaravathi Road, Guntur – 522 002
*Corresponding Author

Published In:   Volume - 2,      Issue - 4,     Year - 2009


ABSTRACT:
A reverse phase high performance liquid chromatographic method (HPLC) has been developed for the estimation of entacapone in its dosage forms using C18 column. The mobile phase (acetonitrile and 20mM potassium dihydrogen phosphate, PH 3.5) was pumped at a flow rate of 1 ml / min in the ratio of 80:20 and the eluents were monitored at 320 nm. The intra- and inter- day variation was found to be less than 2% showing high precision of the assay method. The mean recovery of the drug from the solution containing 200 or 300 ?g / ml was 99.66 ± 1.20% indicating high accuracy. The proposed HPLC method may be used for determining entacapone in bulk drug samples or in pharmaceutical dosage forms.


Cite this article:
P Nagaraju, D Narendra, P Jitendra Kumar, VDN Srinivas, SVN Padma. Determination of Entacapone in Pharmaceutical Preparations by Liquid Chromatography. Asian J. Research Chem. 2(4):Oct.-Dec. 2009 page 454-456.


Recomonded Articles:

Author(s): Vatchavai Bhaskara Raju, Bonthu Mohan Gandhi, Kamatham Srinivas Sumanth, Kolli Srinivas, Tupakula N Venkata Lakshmi Neeraja

DOI: 10.5958/0974-4150.2017.00030.X         Access: Open Access Read More

Author(s): Y. Padmavathi, Akari Anjali, Nayaka Raghavendra Babu, P Ravi Kumar

DOI: 10.5958/0974-4150.2017.00064.5         Access: Open Access Read More

Author(s): Alka Verma, Bhupesh Verma, Sunil Kumar Prajapati, Kishu Tripathi

DOI:         Access: Open Access Read More

Author(s): SS Chitlange, Kiran Bagri, DM Sakarkar

DOI:         Access: Open Access Read More

Author(s): Banerjee S, Bonde CG, Merukar SS, Patil YR

DOI:         Access: Open Access Read More

Author(s): B. Balaswami, P. Venkata Ramana, B. Subba Rao, P. Sanjeeva

DOI: 10.5958/0974-4150.2018.00023.8         Access: Open Access Read More

Author(s): Manorama B. Motegaonkar, S. D. Salunke

DOI: 10.5958/0974-4150.2017.00025.6         Access: Open Access Read More

Author(s): PA Jadhav, CS Raut, JP Bidada, BB Buwa, PN Dhabale, SC Dhawale

DOI:         Access: Open Access Read More

Author(s): R.K. Nanda, S.E. Potawale, V.V. Bhagwat, S.C.Hamane, R. S. Deshmukh

DOI:         Access: Open Access Read More

Author(s): VB Kshirsagar, UA Deokate, VB Bharkad, SS Khadabadi

DOI:         Access: Open Access Read More

Author(s): Tentu Nageswara Rao, Muralidhar Reddy Avuthu, B. Venkata Reddy, SNVS Murthy

DOI: 10.5958/0974-4150.2016.00076.6         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags