A new simple, sensitive, precise, accurate and economical UV spectrophotometric method of analysis for almotriptan malate both as a bulk drug and in tablet formulations was developed and validated. The method employed methanol as solvent and the drug shows maximum absorbance at 227 nm with molar absorptivity of 0.8532×105 L/mol.cm. The linear regression analysis data for the calibration plot showed good linear relationship with r2 = 0.9999 in the concentration range of 1-5 µg/ml. Results of analysis were validated statistically and by recovery studies
Cite this article:
A Suneetha, B Syama Sundar. New Simple UV Spectrophotometric Method for Estimation of Almotriptan Malate in Bulk and Pharmaceutical Dosage Forms. Asian J. Research Chem. 3(1): Jan.-Mar. 2010; Page 142-144.