A simple, sensitive and reproducible spectrophotometric method was developed for the determination of Gemifloxacin (GEMI) in pure and dosage forms. It has absorption maximum at 343nm and obeys beer’s law in the concentration range 2-20 µg mL-1 .Results of analysis were validated statistically and by recovery studies .The apparent molar absorptivity and sandell’s sensitivity were 1.3862 x 104 L mol-1 cm-1 and 2.809 x 10-2 µg cm-2, respectively. The slope and intercept of the equation of the regression line are 0.05370 and -0.00640 respectively. Correlation coefficient was found to be 0.999. This method is successfully employed for the determination of Gemifloxacin in pharmaceutical preparation.
Cite this article:
S. Ganapathy, D.G. Sankar, Pettla Y. Naidu. UV Spectrophotometric Method for the Determination of Gemifloxacin in Bulk and Pharmaceutical Formulation. Asian J. Research Chem. 3(3): July- Sept. 2010; Page 745-746.