P. Sai Praveen, M. Shaiba, S. K. Rasool, T. Srinivasa Rao, D. Prasad Babu
P. Sai Praveen, M. Shaiba*, S. K. Rasool, T. Srinivasa Rao and D. Prasad Babu
K.V.S.R. Siddhartha College of Pharmaceutical Sciences, Siddhartha Nagar, Vijayawada -520010, A.P., India
Volume - 4,
Issue - 1,
Year - 2011
Two simple and sensitive spectrophotometric methods have been developed for the estimation of Milnacipran in pure and pharmaceutical dosage forms. Method A is based on oxidative coupling of the drug with folin-ciocaltaeu reagent (F.C.reagent) ?max780nm. Method B is based on oxidation followed by complex formation when the drug reacts with P-Methylamino phenolsulphate (Metol reagent) ?max 540nm. The absorbance of the colored species is measured against the corresponding reagent blank. These methods have been statistically evaluated and found to be precise and accurate.
Cite this article:
P. Sai Praveen, M. Shaiba, S. K. Rasool, T. Srinivasa Rao, D. Prasad Babu. Spectrophotometric Methods for the Determination of Milnacipran. Asian J. Research Chem. 4(1): January 2011; Page 114-115.