2-chloro-3-formylquinoline undergo cyclo-condensation with 1-naphthylamine in presence of catalytic amount of triethylamine under reflux to afford the corresponding benzo[g]naphtho[b][1,8]naphthyrindes in excellent yields. This procedure provides a convenient method for direct synthesis of benzo and naphtho fused [1,8] naphthyrinde derivatives under thermal conditions. The structure of the synthesized compounds was confirmed by spectral and analytical data.
Cite this article:
V. Nadaraj, S. Thamarai Selvi. Synthesis and Characterization of Naphtho Fused [1,8]Naphthyridine Derivatives. Asian J. Research Chem. 4(1): January 2011; Page 28-30.