ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Pratap Y. Pawar, Kunal N. Jangale

Email(s): pypawar2009@rediffmail.com

DOI: Not Available

Address: Pratap Y. Pawar, Kunal N. Jangale
P.D.V.V.P.F’s College of Pharmacy, Vilad Ghat, Ahmednagar, 414 111, India
*Corresponding Author

Published In:   Volume - 4,      Issue - 11,     Year - 2011


ABSTRACT:
In these study, a series of N2-substituted Dihydrophthalazine-1,4-dione Derivatives (2a-2o) were synthesized from phthalic anhydride and aromatic acid hydrazides (1a-1o) using microwave irradiation. The synthesized compounds were confirmed by IR and1H NMR studies. Synthesized compounds were evaluated for anticonvulsant activity by using maximal electroshock (MES) method. Neurologic deficit was evaluated by the rotarod test. All the compounds exhibited significant anticonvulsant activity. Compounds 2a, 2b, 2i and 2o were most active of the series against MES-induced seizures.


Cite this article:
Pratap Y. Pawar, Kunal N. Jangale. Microwave Assisted Synthesis and Pharmacological Evaluation of N2-substituted Dihydrophthalazine-1,4-dione Derivatives. Asian J. Research Chem. 4(11): Nov., 2011; Page 1722-1725.


Recomonded Articles:

Author(s): Pankaj Baboo, Girendra Gautam, S.K. Gupta

DOI: 10.5958/0974-4150.2017.00039.6         Access: Open Access Read More

Author(s): Suman Bala, Minaxi Saini, Sunil Kamboj, Goldie Uppal, Ashok Kumar

DOI:         Access: Open Access Read More

Author(s): Alok Singh Thakur, Parmanand Verma, Anish Chandy

DOI:         Access: Open Access Read More

Author(s): Shashi Ravi Suman Rudrangi, Vijaya Kumar Bontha, Venkata Reddy Manda, Srinivas Bethi

DOI:         Access: Open Access Read More

Author(s): Deepti Dongarwar Inamdar, Afeez M Dinakaran, Vadiraj D Kurdekar, Hemant R Jadhav

DOI:         Access: Open Access Read More

Author(s): Lingappa Mallesha, Guruswamy Vinay, Bantal Veeresh

DOI: 10.5958/0974-4150.2018.00053.6         Access: Open Access Read More

Author(s): Ajay A. Kharche, Shriram H. Bairagi, Nilesh K. Gorde, Sachin S. Laddha

DOI:         Access: Open Access Read More

Author(s): Pattan Shashikant R, Kekare Prajact, NS Dighe, SB Bhawar, Nikalje Ana, Pati Ashwini, MB Hole

DOI:         Access: Open Access Read More

Author(s): Jignesh P Raval, Hemul V Patel, Pradip S. Patel, Nilesh H Patel, Kishor R Desai

DOI:         Access: Open Access Read More

Author(s): M. Srinivas, Y. Rajendra Prasad, S. Chandrashekaran

DOI:         Access: Open Access Read More

Author(s): U. Sahoo, S. Biswal, S. Sethy, H.K.S. Kumar, M. Banerjee

DOI:         Access: Open Access Read More

Author(s): Siddhartha Marupati, Laxminarayana Eppakayala, Ramesh Malothu, Ramchander Merugu, Venkat Reddy Pendyala

DOI: 10.5958/0974-4150.2017.00099.2         Access: Open Access Read More

Author(s): Monika Bansal, Ramandeep Kaur, Balbir Kaur

DOI:         Access: Open Access Read More

Author(s): Kavitha.K, Nehla Yahoob, Vijayakumar. B,Reshma Fathima.K

DOI: 10.5958/0974-4150.2017.00096.7         Access: Open Access Read More

Author(s): Shashikant R Pattan, Nachiket S Dighe1, Anand A Bukitagar, Prerana A Chavan, Snehlata K Tambe, Deepak S Musmade, S V Hiremath

DOI:         Access: Open Access Read More

Author(s): Sushil R. Mathapati, Vikas B. Suryawanshi,Abhay S. Bondge,Jairaj K. Dawale

DOI: 10.5958/0974-4150.2018.00044.5         Access: Open Access Read More

Author(s): VA Navale, SS Mokle, Archana Y Vibhute, KG Karamunge, SV Khansole, SB Junne, YB Vibhute

DOI:         Access: Open Access Read More

Author(s): Kishore U. Kothule, Prashant Kesharwani, Rakesh R. Somani, Prabhakar Y. Shirodkar

DOI:         Access: Open Access Read More

Author(s): P Muthumani, R Meera, Pratesh, N Chidambaranathan, P Devi, Bkameswari

DOI:         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags