ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): U. Sahoo, S. Biswal, S. Sethy, H.K.S. Kumar, M. Banerjee

Email(s): uks1998@gmail.com

DOI: Not Available

Address: U. Sahoo1*, S. Biswal1, S. Sethy1, H.K.S. Kumar1 and M. Banerjee1
Department of Medicinal Chemistry, Institute of Pharmacy and Technology, Salipur, Cuttack, Odisha-754202
*Corresponding Author

Published In:   Volume - 5,      Issue - 2,     Year - 2012


ABSTRACT:
Imidazole is a planer five-member heterocyclic ring with 3C and 2N atom and in ring N is present in 1st and 3rd positions. The imidazole ring is a constituent of several important natural products, including purine, histamine, histidine and nucleic acid. Being a polar and ionisable aromatic compound, it improves pharmacokinetic characteristics of lead molecules and thus used as a remedy to optimize solubility and bioavailability parameters of proposed poorly soluble lead molecules. Imidazole derivatives have occupied a unique place in the field of medicinal chemistry. The incorporation of the imidazole nucleus is an important synthetic strategy in drug discovery. The high therapeutic properties of the imidazole related drugs have encouraged the medicinal chemists to synthesize a large number of novel chemotherapeutic agents. Imidazole drugs have broadened scope in remedying various dispositions in clinical medicines. Numerous methods for the synthesis of imidazole and also their various structure reactions offer enormous scope in the field of medicinal chemistry. This articles aims to review the work reported, their chemistry and biological activities of imidazole during past years.


Cite this article:
U. Sahoo, S. Biswal, S. Sethy, H.K.S. Kumar, M. Banerjee. Imidazole and its Biological Activities: A Review. Asian J. Research Chem. 5(2): February 2012; Page 171-182.


Recomonded Articles:

Author(s): Virupakshi Prabhakar, Kondra Sudhakar Babu, L.K. Ravindranath, M. Sahanoor Basha, J. Latha

DOI: 10.5958/0974-4150.2017.00012.8         Access: Open Access Read More

Author(s): Ram C. Senwar, Krishna K. Rathore, Anita Mehta

DOI: 10.5958/0974-4150.2017.00022.0         Access: Open Access Read More

Author(s): Arun Kumar, Vinita Gupta, Sanchita Singh, Y.K. Gupta

DOI: 10.5958/0974-4150.2017.00038.4         Access: Open Access Read More

Author(s): Tauseef Shaikh, Atar Mujum , Khan Wasimuzzama, Rukhsana A Rub

DOI:         Access: Open Access Read More

Author(s): Prathima Patil, S.P. Sethy, T. Sameena, K. Shailaja

DOI:         Access: Open Access Read More

Author(s): Alka Verma, Bhupesh Verma, Sunil Kumar Prajapati, Kishu Tripathi

DOI:         Access: Open Access Read More

Author(s): Pankaj Baboo, Girendra Gautam, S.K. Gupta

DOI: 10.5958/0974-4150.2017.00039.6         Access: Open Access Read More

Author(s): Maqdoom Farooqui, Syed Nazimuddin

DOI: 10.5958/0974-4150.2017.00026.8         Access: Open Access Read More

Author(s): Gangadhara MM, Dinesha R, Satish Kumar Murari

DOI: 10.5958/0974-4150.2017.00020.7         Access: Open Access Read More

Author(s): Suman Bala, Minaxi Saini, Sunil Kamboj, Goldie Uppal, Ashok Kumar

DOI:         Access: Open Access Read More

Author(s): Virupakshi Prabhakar, K. Sudhakar Babu, . L. K. Ravindranath, B.Venkateswarlu

DOI: 10.5958/0974-4150.2017.00035.9         Access: Open Access Read More

Author(s): KP Bhusari, ND Amnerkar, PB Khedekar, MK Kale, RP Bhole

DOI:         Access: Open Access Read More

Author(s): SR Pattan, NS Dighe, SA Nirmal, AN Merekar, RB Laware, HV Shinde, DS Musmade

DOI:         Access: Open Access Read More

Author(s): S.B. Junne, Archana B. Kadam, Archana Y. Vibhute, S.L. Shinde, R.B. Patil, Y.B. Vibhute

DOI:         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags