The acid hydrazides (I and IV) were condensed with indole-2,3-dione in ethanol to yield hydrazono-indolin-2-ones (II and V) which on aminomethylation with formaldehyde and different amines furnished 1-(substituted aminomethyl)-hydrazono-indolin-2-ones (IIIa-e and VIa-e). The structures of the newly synthesized compounds have been confirmed by IR, 1H NMR and Mass spectra. These compounds have shown promising biological activity.
Cite this article:
Freddy H. Havaldar, Azadkumar S. Sharma, Peter Roni F. Pinto. Synthesis of New Indoline-2-Ones and Their Microbial Activity. Asian J. Research Chem. 4(12): Dec., 2011; Page 1840-1803.