ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Atul Srivastav, Shishir Maheshwari

Email(s): atulpharma21690@gmail.com

DOI: Not Available

Address: Atul Srivastav*, Shishir Maheshwari
Department of Pharmaceutical Chemistry, IIMT College of Medical Sciences, Meerut-250001
*Corresponding Author

Published In:   Volume - 7,      Issue - 1,     Year - 2014


ABSTRACT:
A simple, sensitive, precise and specific UV spectrophotometric method for Multicomponent Mode of Metformin HCl and Metformin in combine dosage form has been developed. The wavelengths 233 nm and 228 nm were selected for the estimation of Metformin HCl and Glimepiride respectively, where Acetonitrile was used as solvent. Linearity were observed in the concentration range of 5-10 µg/ml (r2=0.999) and 3-18 µg/ml (r2=0.999) for Metformin HCl and Glimepiride. These methods were validated according to ICH guidelines.


Cite this article:
Atul Srivastav, Shishir Maheshwari. Development and Validation of Multi-Component Mode UV Spectrophotometric Method for the Estimation of Metformin and Glimepiride in Combined Dosage Form. Asian J. Research Chem. 7(1): January 2014; Page 07-10.


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