ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Atul Bajaj, Cijo John

Email(s): atulbajaj37@gmail.com

DOI: 10.5958/0974-4150.2015.00065.6   

Address: Atul Bajaj*, Cijo John
Central Forensic Science Laboratory, Plot No 2, Sector 36 A, Dakshin Marg, Ministry of Home Affairs, Govt. of India, Chandigarh, India-160 036
*Corresponding Author

Published In:   Volume - 8,      Issue - 6,     Year - 2015


ABSTRACT:
A new simple, reliable and selective Thin-Layer Chromatographic (TLC) method has been developed for the simultaneous determination of four common p- hydroxy benzoates (parabens); methyl paraben (MP), ethyl paraben (EP), propyl paraben (PP) and butyl paraben (BP) using mobile phase in basic medium on silica gel F254 stationary phase. Detection was carried out with newly developed chromogenic visualisation reagent. Studies for minimum detection limit of the compounds were performed with new method. The detection limit for all these compounds with new chromogenic visualisation reagent were in the range of 0.4-0.8 (µg/spot). The method gave reproducible results and was successfully applied to simultaneous determination of these compounds in commercially available personal care products and pharmaceutical preparations. The separation method is inexpensive and reliable.


Cite this article:
Atul Bajaj, Cijo John. Simultaneous Determination of p-Hydroxybenzoate Preservatives in Pharmaceuticals and Personal Care Formulations. Asian J. Research Chem 8(6): June 2015; Page 394-398. doi: 10.5958/0974-4150.2015.00065.6


Recomonded Articles:

Author(s): Vatchavai Bhaskara Raju, Bonthu Mohan Gandhi, Kamatham Srinivas Sumanth, Kolli Srinivas, Tupakula N Venkata Lakshmi Neeraja

DOI: 10.5958/0974-4150.2017.00030.X         Access: Open Access Read More

Author(s): Y. Padmavathi, Akari Anjali, Nayaka Raghavendra Babu, P Ravi Kumar

DOI: 10.5958/0974-4150.2017.00064.5         Access: Open Access Read More

Author(s): Alka Verma, Bhupesh Verma, Sunil Kumar Prajapati, Kishu Tripathi

DOI:         Access: Open Access Read More

Author(s): SS Chitlange, Kiran Bagri, DM Sakarkar

DOI:         Access: Open Access Read More

Author(s): Banerjee S, Bonde CG, Merukar SS, Patil YR

DOI:         Access: Open Access Read More

Author(s): Tripti Jain, V Jain, R Pandey, A Vyas, SS Shukla

DOI:         Access: Open Access Read More

Author(s): Manorama B. Motegaonkar, S. D. Salunke

DOI: 10.5958/0974-4150.2017.00025.6         Access: Open Access Read More

Author(s): PA Jadhav, CS Raut, JP Bidada, BB Buwa, PN Dhabale, SC Dhawale

DOI:         Access: Open Access Read More

Author(s): VB Kshirsagar, UA Deokate, VB Bharkad, SS Khadabadi

DOI:         Access: Open Access Read More

Author(s): Tentu Nageswara Rao, Muralidhar Reddy Avuthu, B. Venkata Reddy, SNVS Murthy

DOI: 10.5958/0974-4150.2016.00076.6         Access: Open Access Read More

Author(s): Sravani A

DOI: 10.5958/0974-4150.2018.00144.X         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags