Coupling of Single-Stranded poly-T DNA with Small Heterocyclic compounds via Peptide Linkage

Souvik Sur

doi:10.52711/0974-4150.2024.00016

Asian Journal of Research in Chemistry

ISSN

0974-4150 (Online)
0974-4169 (Print)

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Coupling of Single-Stranded poly-T DNA with Small Heterocyclic compounds via Peptide Linkage

Author(s): Souvik Sur

Email(s): drsouvik.engineering@tmu.ac.in

DOI: 10.52711/0974-4150.2024.00016

Address: Souvik Sur*
Research and Development Center, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh - 244001, India.
*Corresponding Author

Published In: Volume - 17, Issue - 2, Year - 2024

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ABSTRACT:
This study introduces a versatile method for coupling single-stranded DNA with small heterocyclic compounds, leveraging the reactivity of amino and carboxylic functional groups. By employing COMU and Collidine, BNIMZ and BNTZA were successfully coupled with poly-T DNA. The conjugation technique was successfully confirmed by high accuracy MALDI-TOF MS. This approach offers a reliable and efficient strategy for constructing DNA-conjugates with tailored properties.

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Cite this article:
Souvik Sur. Coupling of Single-Stranded poly-T DNA with Small Heterocyclic compounds via Peptide Linkage. Asian Journal of Research in Chemistry. 2024; 17(2):81-4. doi: 10.52711/0974-4150.2024.00016

Cite(Electronic):
Souvik Sur. Coupling of Single-Stranded poly-T DNA with Small Heterocyclic compounds via Peptide Linkage. Asian Journal of Research in Chemistry. 2024; 17(2):81-4. doi: 10.52711/0974-4150.2024.00016 Available on: https://ajrconline.org/AbstractView.aspx?PID=2024-17-2-4

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