ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Soram Ibomcha Singh, Shashi Prabha

Email(s): ibomsoram@yahoo.co.uk

DOI: Not Available

Address: Soram Ibomcha Singh and Shashi Prabha*
School of Studies in Chemistry, Jiwaji University, Gwalior-474011
*Corresponding Author

Published In:   Volume - 2,      Issue - 4,     Year - 2009


ABSTRACT:
Phosphoramidates (N-P) are biologically active organic compounds because they are capable of inhibiting enzyme action. A few members of this class were synthesized and checked for their anticholinesterase properties and they were found to be a good reactive phosphorylating agent to block AChE rather than BuChE in the poisoning process. The presence of chloro-substituent (either ortho- or para-) in the aryl moiety of these phosphoramidates does not show any significant contribution during toxicological study made in vitro. These phosphoramidates were characterized by FT-IR, 31P NMR and GC-MS spectral studies.


Cite this article:
Soram Ibomcha Singh, Shashi Prabha. Synthesis, Identification of Some P-Chiral Organic Phosphoramidates and Their Inhibitory Action towards Enzymes. Asian J. Research Chem. 2(4):Oct.-Dec. 2009 page 523-525.


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