Poonam R. Faldu, Sandip K. Dadhaniya, Chirag J.Patel, G. Vidyasagar
Poonam R. Faldu1*, Sandip K. Dadhaniya2, Chirag J.Patel1 and G. Vidyasagar1
1 Veerayatan Institute of Pharmacy, Mandvi- Kutch, Gujarat
2R.B. Patel Mahila Pharmacy College, Atkot, Gujarat.
Volume - 4,
Issue - 12,
Year - 2011
Multicomponent reactions (MCRs) provide a powerful tool towards the one-pot synthesis of diverse and complex compounds on the one hand and small and ‘drug-like’ heterocycles on the other hand. No other single synthesis technology enables chemists to search such large chemical spaces as provided by MCRs. This review describes various three component and four component reaction example and recent advances in the application of isocyanide-based multicomponent reactions (IMCRs) in drug discovery.
Cite this article:
Poonam R. Faldu, Sandip K. Dadhaniya, Chirag J.Patel, G. Vidyasagar. Multi-Component Reaction and Their Application in Drug Discovery. Asian J. Research Chem. 4(12): Dec., 2011; Page 1818-1824.