Asian Journal of Research in Chemistry

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0974-4150 (Online)
0974-4169 (Print)


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Multi-Component Reaction and Their Application in Drug Discovery

Author(s): Poonam R. Faldu, Sandip K. Dadhaniya, Chirag J.Patel, G. Vidyasagar

Email(s): faldupoonam@gmail.com

DOI: Not Available

Address: Poonam R. Faldu1*, Sandip K. Dadhaniya2, Chirag J.Patel1 and G. Vidyasagar1
1 Veerayatan Institute of Pharmacy, Mandvi- Kutch, Gujarat
2R.B. Patel Mahila Pharmacy College, Atkot, Gujarat.
*Corresponding Author

Published In:   Volume - 4,      Issue - 12,     Year - 2011

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ABSTRACT:
Multicomponent reactions (MCRs) provide a powerful tool towards the one-pot synthesis of diverse and complex compounds on the one hand and small and ‘drug-like’ heterocycles on the other hand. No other single synthesis technology enables chemists to search such large chemical spaces as provided by MCRs. This review describes various three component and four component reaction example and recent advances in the application of isocyanide-based multicomponent reactions (IMCRs) in drug discovery.


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Cite this article:
Poonam R. Faldu, Sandip K. Dadhaniya, Chirag J.Patel, G. Vidyasagar. Multi-Component Reaction and Their Application in Drug Discovery. Asian J. Research Chem. 4(12): Dec., 2011; Page 1818-1824.

Cite(Electronic):
Poonam R. Faldu, Sandip K. Dadhaniya, Chirag J.Patel, G. Vidyasagar. Multi-Component Reaction and Their Application in Drug Discovery. Asian J. Research Chem. 4(12): Dec., 2011; Page 1818-1824.   Available on: https://ajrconline.org/AbstractView.aspx?PID=2011-4-12-3


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Asian Journal of Research in Chemistry (AJRC) (ISSN: print-0974-4169, Online-0974-4150) is an international, peer-reviewed journal devoted to pure and applied chemistry. AJRC publishes Original Research Articles, Short Communications, Review Articles in all aspects of chemistry. Topics covered including the traditional areas of analytical, inorganic, organic, biochemistry, forensic, physical-theoretical chemistry as well as newer interdisciplinary areas such as agriculture, materials science, computational, medicine, spectroscopy, polymers, supramolecular, surface, chemical physics, biological, medicinal/ drugs, environmental and pharmaceutical chemistry.
The journal is published quarterly every year in last week of March, June, September and December. From January 2011, is monthly and shall be published every year in last week of Month.    
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