ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Pratap Y. Pawar, Manisha P. Chavan

Email(s): pawarpy2001@yahoo.co.in

DOI: Not Available

Address: Pratap Y. Pawar* and Manisha P. Chavan
Department of Pharmaceutical Chemistry, Padmashree Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahmednagar, MS, India
Corresponding author

Published In:   Volume - 5,      Issue - 1,     Year - 2012


ABSTRACT:
A series of phthalimide derivatives were synthesized and evaluated for their analgesic and invitro antiinflammatory activity. The target compounds were obtained by condensation of N-hydroxymethylphthalimide with the substituted thiadiazole. The structures of the synthesized derivatives were confirmed by means of IR, 1H-NMR spectral data. The analgesic activity was determined by acetic acid induced writhings in mice and Invitro antiinflammatory activity was evaluated using thermally induced protein denaturation technique. The results revealed the importance of the combination of thiadiazole and phthalimide moieties as a promising analgesic and antiinflammatory candidate.


Cite this article:
Pratap Y. Pawar, Manisha P. Chavan. Synthesis and Pharmacological Evaluation of 1, 3-Isoindolinedione Derivatives as Analgesic and Antiinflammatory Agents. Asian J. Research Chem. 5(1): January 2012; Page 127-130.

Cite(Electronic):
Pratap Y. Pawar, Manisha P. Chavan. Synthesis and Pharmacological Evaluation of 1, 3-Isoindolinedione Derivatives as Analgesic and Antiinflammatory Agents. Asian J. Research Chem. 5(1): January 2012; Page 127-130.   Available on: https://ajrconline.org/AbstractView.aspx?PID=2012-5-1-25


Recomonded Articles:

Author(s): Suman Bala, Minaxi Saini, Sunil Kamboj, Goldie Uppal, Ashok Kumar

DOI:         Access: Open Access Read More

Author(s): Kishore Kumar Valluri, Tejeswara Rao Allaka, I V Kasi Viswanath, Nagaraju PVVS

DOI: 10.5958/0974-4150.2018.00111.6         Access: Open Access Read More

Author(s): Pankaj Gupta, Hardwari Lal Yadav, G. Garg, R.S. Pawar, U.K. Patil, P.K. Singour

DOI:         Access: Open Access Read More

Author(s): P.A. Patil, R.P. Bhole, R.V. Chikhale, K.P. Bhusari, Amol Chandekar

DOI:         Access: Open Access Read More

Author(s): Ajay A. Kharche, Shriram H. Bairagi, Nilesh K. Gorde, Sachin S. Laddha

DOI:         Access: Open Access Read More

Author(s): Rakesh Saini, Saurabh Chaturvedi, AN Kesari, Rijuved Garg, Amita Verma

DOI:         Access: Open Access Read More

Author(s): HG Akkamma, BS Vikram, T Srinivas Rao, D Baggiya Selvi

DOI:         Access: Open Access Read More

Author(s): Snehal A. Rokade, Rupali. V. Jadhav

DOI: 10.52711/0974-4150.2022.00075         Access: Open Access Read More

Author(s): Alok Pandey, Shekhar Verma, Ravindra Dhar Dubey, Dhansay Dewangan, Vidyanand Patel, Keshav Deshmukh

DOI:         Access: Open Access Read More

Author(s): Harsha Tripathy, Krishananand ST, Laxmi Adhikary, Chandrashekhar J

DOI:         Access: Open Access Read More

Author(s): Harsha Tripathy, Krishananand ST, Laxmi Adhikary, Chandrashekhar J

DOI:         Access: Open Access Read More

Author(s): Ramesh V., S.M. Shantakumar, M. Bhagavanraju

DOI:         Access: Open Access Read More

Author(s): Deepak Lande, Meenakshi Deodhar, Ashok Bhosle, Ganesh Bhawal

DOI:         Access: Open Access Read More

Author(s): Harer Sunil L, Rajurkar Vikas G, Kardile Nitin, Harer Priyanka S

DOI:         Access: Open Access Read More

Author(s): Biplab De, Sandip Sen, T.S. Easwari

DOI: 10.5958/0974-4150.2015.00069.3         Access: Open Access Read More

Author(s): Rajesh B, Ramasubbualakshmi A, Gopalasatheeskumar K, Bharathi D, Nishanth R

DOI: 10.5958/0974-4150.2020.00030.9         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags