Asian Journal of Research in Chemistry

ISSN

0974-4150 (Online)
0974-4169 (Print)


Submit Article

Chemometrics-assisted Spectrophotometric Determination of Ciprofloxacin and Naphazoline in Eye Drops

Author(s): Vu Dang Hoang

Email(s): hoangvd@hup.edu.vn

DOI: Not Available

Address: Vu Dang Hoang
Department of Analytical Chemistry and Toxicology, Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Vietnam
*Corresponding Author

Published In:   Volume - 7,      Issue - 5,     Year - 2014

 View HTML        View PDF

ABSTRACT:
Multivariate calibration methods (Classical Least Squares, Inverse Least Squares and Principal Component Analysis) using the absorption spectra in the region of 225 – 265 nm were proposed for the resolution of strongly overlapping spectra of Ciprofloxacin and Naphazoline in binary mixtures. The quantitative predictive abilities of these methods were evaluated by the use of calibration matrix with nine synthetic mixtures of both compounds (24–36 mg/L of Ciprofloxacin and 4 – 6 mg/L of Naphazoline). They were also successfully applied to the simultaneous determination of Ciprofloxacin and Naphazoline in commercially available eye drops. Their performances were statistically compared by one-way ANOVA and Bartlett tests clearly indicating their similar accuracy and precision.


Keywords:

Cite this article:
Vu Dang Hoang. Chemometrics-assisted Spectrophotometric Determination of Ciprofloxacin and Naphazoline in Eye Drops. Asian J. Research Chem. 7(5): May 2014; Page 461-465.

Cite(Electronic):
Vu Dang Hoang. Chemometrics-assisted Spectrophotometric Determination of Ciprofloxacin and Naphazoline in Eye Drops. Asian J. Research Chem. 7(5): May 2014; Page 461-465.   Available on: https://ajrconline.org/AbstractView.aspx?PID=2014-7-5-1


Recomonded Articles:

Antibacterial Screening of Clerodendrum infortunatum leaves: Experimental and Molecular docking studies

Author(s): Sindhu. T. J, Akhilesh K. J, Anju. Jose, Binsiya K. P, Blessy Thomas, Elizabeth Wilson

DOI: 10.5958/0974-4150.2020.00026.7         Access: Open Access Read More

A Simple UV Spectrophotometric Method Development and Validation for Estimation of Ciprofloxacin Hydrochloride in Bulk and Tablet Dosage Form

Author(s): Singh Kumar Rakesh, Patel Singh Pankaj, Singh Amar, Roy R.K.

DOI:         Access: Open Access Read More

Synthesis, Characterization, Equilibrium Studies and Antibacterial Studies of Co(II) complex with Schiff base Ligand derived from Pyridoxal and 2,4-Dichlorobenzohydrazide

Author(s): Kavitha R., Ch. Venkata Ramana Reddy, B. Sireesha

DOI: 10.5958/0974-4150.2017.00047.5         Access: Open Access Read More

Synthesis, Characterization and Biological Evaluation of Ciprofloxacin N-N Donor Metal Complex

Author(s): Prafulla M Sabale, Dhiraj S Bhagwat, Karan Parwe

DOI: 10.5958/0974-4150.2018.00105.0         Access: Open Access Read More

Estimation of Tadalafil in Bulk and in Formulation by UV-Visible Spectrophotometry

Author(s): K Anandakumar, K Varadharajan, R Subathrai, D Jothieswari, G Sivan Seyal

DOI:         Access: Open Access Read More

Synthesis of Aromatic Heterocyclic Ketimines: Part-II. Synthesis, Characterization and Biological Studies of Copper complex of Biomolecule

Author(s): C. J. Patil, M. C. Patil, N. A. Patil, Dhiraj Kolhe

DOI: 10.5958/0974-4150.2017.00065.7         Access: Open Access Read More

Computational Study of Corrosion Potential of Ciprofloxacin Drug: DFT Approach

Author(s): Jeetendra Bhawsar, P.K. Jain, Preeti Jain, Mukta Rani Bhawsar

DOI:         Access: Open Access Read More

Determination of Tropicamide and Hydroxyamphetamine in Opthalmic formulations by RP-HPLC and its Validation

Author(s): Devadasu Ch, Sravya G

DOI: 10.5958/0974-4150.2021.00003.1         Access: Open Access Read More

Target Oriented Selective Synthesis of Antibacterial Active Tyrosinase Enzyme Inhibitor Coumarin Core Derivatives

Author(s): Digambar Kumbhar, Reshma Patil, Dayanand Patil, Ajinkya Patravale, Dattatray Chandam, Sunetra Jadhav, Dattatray Chavan, Prafulla Choudhari, Manish Bhatia, Madhukar Deshmukh

DOI: 10.5958/0974-4150.2015.00081.4         Access: Open Access Read More

Synthesis, Characterization and Biological Activity of Schiff Base Metal Complexes

Author(s): Gundu Mallikarjun

DOI: 10.5958/0974-4150.2017.00098.0         Access: Open Access Read More

Antibacterial, Anthelmintic, Analgesic and Anti-Inflammatory Activity of Conventional and Microwave Assisted Synthesized 3-(Substituted)-2-Phenylquinazolin-4(3h)-One

Author(s): Subal Debnath, S.Y. Manjunath

DOI:         Access: Open Access Read More

Simultaneous Determination of Ciprofloxacin Hydrochloride and Dexamethasone in Ophthalmic Solution by Reversed Phase High Performance Liquid Chromatography

Author(s): Rele R.V.., Warkar C.B.

DOI:         Access: Open Access Read More

Microwave Assisted Synthesis and Antibacterial Activity of Some Bicyclic Pyrrolidines

Author(s): M. Srinivas, Y. Rajendra Prasad, S. Chandrashekaran

DOI:         Access: Open Access Read More

Quantitative Determination of Drugs by using Chloramine-T and Methyl orange Couple: A spectrophotometric study

Author(s): M. Sasikala, K. Sayanna, G. Venkateshwarlu

DOI: 10.5958/0974-4150.2015.00021.8         Access: Open Access Read More

Ion-Pair Spectrophotometric Estimation of Ciprofloxacin in bulk and pharmaceutical formulations

Author(s): A. S. Grewal, S. K. Patro, S. K. Kanungo

DOI:         Access: Open Access Read More

Simultaneous RP-HPLC Estimation of Ciprofloxacin Hydrochloride and Ornidazole in Tablet Dosage Form

Author(s): I. Carolin Nimila, P. Balan, R. Sathiya Sundar, J. Ashok Kumar, S. Rajasekar

DOI:         Access: Open Access Read More

Synthesis, characterization, thermal and antibacterial studies of organosilicon (IV) and organotin (IV) complexes derived from Schiff base ligand

Author(s): Jai Devi, Suman Devi

DOI: 10.5958/0974-4150.2016.00063.8         Access: Open Access Read More

Molecular Modification in Fluoroquinolones

Author(s): Pandeya S.N, Ranjana, Neha Rajput

DOI:         Access: Open Access Read More

Synthesis and Antibacterial Activity of 4-chloro-2-phenyl quinoline Derivatives

Author(s): A. R. Chabukswar, B.S.Kuchekar, P.D.Lokhande, V.V. Chabukswar, S.D. Tambe, M.N. Mohokar, B.D. Pagare

DOI:         Access: Open Access Read More

Chemometrics-assisted Spectrophotometric Determination of Ciprofloxacin and Naphazoline in Eye Drops

Author(s): Vu Dang Hoang

DOI:         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Quick Links

Latest Issues

Popular Articles


Recent Articles



Activated carbon from macadamia nutshells for removal of p-Nitrophenol from real wastewater: Thermodynamic evaluation
Review on Colon Targeted Drug Delivery System
Exploring the Effects of Polyacrylic Acid on Triton-X-100 Aqueous Solutions: Density, Viscosity and Ultrasonic Velocity Analysis
Formulation and Evaluation of Amaranthus dubius herbal gel
Estimation of Imatinib Mesylate by Extractive Colorimetric Methods in Bulk and Pharmaceutical Dosage Form
Qualitative and Quantitative Analysis of the Phytochemicals in Aerva lanata
Co-Solvent effect and Kinetics of Alkaline Hydrolysis of Butyle Salicylate
A Systematic Review on Ethnobotanical and Pharmacological Aspects of Croton plant Codiaeum variegatum (L.)
Review on Thiazolo-Triazole as a Promising Anticancer agent
Inimical effects of Monosodium Glutamate on various systems
Synthesis and Surface properties of LABSA Based detergents: An Ecofriendly Approach
A mini Review on Analytical and Bioanlytical Techniques in Study of Drugs-Protein Interaction
Review on Vesicular Drug Delivery System: Aquasomes
Synthesis, Characterization and Antioxidant Activity of some New Antipyrine derived Schiff Bases
Determination of Imatinib mesylate from Pharmaceutical Dosage Form by extractive ion pair complex colorimetric Method
Coupling of Single-Stranded poly-T DNA with Small Heterocyclic compounds via Peptide Linkage
Determination of Methdilazine by Extractive Colorimetric Method from Pharmaceutical Dosage Form
Synthesis and Surface properties of AOS Based detergents: A Green Synthetic approach
Bioanalytical Method Development and Validation of UV Spectrophotometric Method for Estimation of Metformin Hydrochloride in Urine Sample
Oxovanadium (IV) Complexes of α-Amino Acid Schiff Bases and 2,2

Tags


About Journal

Asian Journal of Research in Chemistry (AJRC) (ISSN: print-0974-4169, Online-0974-4150) is an international, peer-reviewed journal devoted to pure and applied chemistry. AJRC publishes Original Research Articles, Short Communications, Review Articles in all aspects of chemistry. Topics covered including the traditional areas of analytical, inorganic, organic, biochemistry, forensic, physical-theoretical chemistry as well as newer interdisciplinary areas such as agriculture, materials science, computational, medicine, spectroscopy, polymers, supramolecular, surface, chemical physics, biological, medicinal/ drugs, environmental and pharmaceutical chemistry.
The journal is published quarterly every year in last week of March, June, September and December. From January 2011, is monthly and shall be published every year in last week of Month.    
Read More  

Visitors

Today: 806
Yesterday: 1438
Total: 1599202