Author(s):
Narasimha Murthy Kotra, Buchi Reddy Reguri, Mukkanti Khagga
Email(s):
kotramurthy@hotmail.com
DOI:
10.5958/0974-4150.2015.00032.2 
Address:
Narasimha Murthy Kotra1*, Buchi Reddy Reguri2 , Mukkanti Khagga3
1,3Center for Chemical Science and Technology, JNT University, Kukatpally, Hyderabad
2PCA Laboratories Ltd, Kandivali, Industrial Estate, Mumbai, India
*Corresponding Author
Published In:
Volume - 8,
Issue - 3,
Year - 2015
ABSTRACT:
An alternative synthesis of amidoalkyl naphthols, employing a four-component reaction of aryl aldehydes, enolisable ketones, acetyl chloride and acetonitrile to form the corresponding ß-acetylamino ketones at room temperature in the presence of a catalytic amount of tetrabutyl ammonium hydrogen sulphate (TBAHS) has been described. The present procedure offers advantages such as shorter reaction time, simple workup with excellent yields. This simple procedure combined with the easy recovery and reuse of the catalyst makes this method economic, benign and a greener chemical process for the synthesis of ß-acetamido ketones.
Cite this article:
Narasimha Murthy Kotra, Buchi Reddy Reguri, Mukkanti Khagga. TBAHS Catalyzed Synthesis of β-Acetamido Ketones/ Esters. Asian J. Research Chem 8(3): March 2015; Page 179-182. doi: 10.5958/0974-4150.2015.00032.2
Cite(Electronic):
Narasimha Murthy Kotra, Buchi Reddy Reguri, Mukkanti Khagga. TBAHS Catalyzed Synthesis of β-Acetamido Ketones/ Esters. Asian J. Research Chem 8(3): March 2015; Page 179-182. doi: 10.5958/0974-4150.2015.00032.2 Available on: https://ajrconline.org/AbstractView.aspx?PID=2015-8-3-6