Asian Journal of Research in Chemistry

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0974-4150 (Online)
0974-4169 (Print)


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CuCl2.2H2O-Catalysed One-Pot Multi-Component Synthesis of β-Acetamido Ketones

Author(s): Rajat S. Pathak, Amiya Shekhar, Devendra D. Pathak

Email(s): ddpathak@yahoo.com

DOI: Not Available

Address: Rajat S. Pathak, Amiya Shekhar and Devendra D. Pathak*
Department of Applied Chemistry, Indian School of Mines, Dhanbad-826004, Jharkhand, India
*Corresponding Author

Published In:   Volume - 4,      Issue - 12,     Year - 2011

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ABSTRACT:
One pot, four-component condensation of an aryl aldehyde, acetyl chloride, acetophenone and acetonitrile in the presence of Copper(II) chloride dihydrate is reported. Copper(II) chloride as an inexpensive, efficient, and readily available catalyst for the synthesis of ß-acetamido ketones in high yields. The products obtained were clean and devoid of any undesired impurities as evident from 1H NMR, IR, and TLC analysis.


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Cite this article:
Rajat S. Pathak, Amiya Shekhar, Devendra D. Pathak. CuCl2.2H2O-Catalysed One-Pot Multi-Component Synthesis of β-Acetamido Ketones. Asian J. Research Chem. 4(12): Dec., 2011; Page 1930-1934.

Cite(Electronic):
Rajat S. Pathak, Amiya Shekhar, Devendra D. Pathak. CuCl2.2H2O-Catalysed One-Pot Multi-Component Synthesis of β-Acetamido Ketones. Asian J. Research Chem. 4(12): Dec., 2011; Page 1930-1934.   Available on: https://ajrconline.org/AbstractView.aspx?PID=2011-4-12-27


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Asian Journal of Research in Chemistry (AJRC) (ISSN: print-0974-4169, Online-0974-4150) is an international, peer-reviewed journal devoted to pure and applied chemistry. AJRC publishes Original Research Articles, Short Communications, Review Articles in all aspects of chemistry. Topics covered including the traditional areas of analytical, inorganic, organic, biochemistry, forensic, physical-theoretical chemistry as well as newer interdisciplinary areas such as agriculture, materials science, computational, medicine, spectroscopy, polymers, supramolecular, surface, chemical physics, biological, medicinal/ drugs, environmental and pharmaceutical chemistry.
The journal is published quarterly every year in last week of March, June, September and December. From January 2011, is monthly and shall be published every year in last week of Month.    
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